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RNA-splicing ligase RtcB [Salmonella enterica].


LOCUS       WP_001541599             405 aa            linear   BCT 24-AUG-2020
ACCESSION   WP_001541599
VERSION     WP_001541599.1
KEYWORDS    RefSeq.
SOURCE      Salmonella enterica
  ORGANISM  Salmonella enterica
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Salmonella.
REFERENCE   1  (residues 1 to 405)
  AUTHORS   Maughan,W.P. and Shuman,S.
  TITLE     Distinct Contributions of Enzymic Functional Groups to the
            2',3'-Cyclic Phosphodiesterase, 3'-Phosphate Guanylylation, and
            3'-ppG/5'-OH Ligation Steps of the Escherichia coli RtcB Nucleic
            Acid Splicing Pathway
  JOURNAL   J. Bacteriol. 198 (8), 1294-1304 (2016)
   PUBMED   26858100
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 405)
  AUTHORS   Chakravarty,A.K. and Shuman,S.
  TITLE     The sequential 2',3'-cyclic phosphodiesterase and
            3'-phosphate/5'-OH ligation steps of the RtcB RNA splicing pathway
            are GTP-dependent
  JOURNAL   Nucleic Acids Res. 40 (17), 8558-8567 (2012)
   PUBMED   22730297
REFERENCE   3  (residues 1 to 405)
  AUTHORS   Chakravarty,A.K., Subbotin,R., Chait,B.T. and Shuman,S.
  TITLE     RNA ligase RtcB splices 3'-phosphate and 5'-OH ends via covalent
            RtcB-(histidinyl)-GMP and polynucleotide-(3')pp(5')G intermediates
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 109 (16), 6072-6077 (2012)
   PUBMED   22474365
REFERENCE   4  (residues 1 to 405)
  AUTHORS   Tanaka,N., Chakravarty,A.K., Maughan,B. and Shuman,S.
  TITLE     Novel mechanism of RNA repair by RtcB via sequential 2',3'-cyclic
            phosphodiesterase and 3'-Phosphate/5'-hydroxyl ligation reactions
  JOURNAL   J. Biol. Chem. 286 (50), 43134-43143 (2011)
   PUBMED   22045815
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR011253
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..405
                     /organism="Salmonella enterica"
                     /db_xref="taxon:28901"
     gene            1..405
                     /gene="rtcB"
     Protein         1..405
                     /product="RNA-splicing ligase RtcB"
                     /EC_number="6.5.1.8"
                     /calculated_mol_wt=44653
     Region          9..405
                     /region_name="RtcB"
                     /note="RNA-splicing ligase RtcB, repairs tRNA damage
                     [Translation, ribosomal structure and biogenesis];
                     COG1690"
                     /db_xref="CDD:441296"
ORIGIN      
        1 mmnyelmttq napvkmwtkg vpveddarqq lintakmpfi fkhiavmpdv hlgkgstigs
       61 viptkgaiip aavgvdigcg mnalrtslta adlpenladl rsaieaavph grttgrghrd
      121 vgawgnppan vnekwaqlea gyqwltqkyp rflntnnykh lgtlgtgnhf ieicldetdr
      181 vwimlhsgsr gignaigtyf iglaqqemqe qletlpsrdl ayfnegseyf ddylkavhwa
      241 qqfaslnrea mmenalaalq rcvekpsald mdeinchhny vqkeqhfgee iyvtrkgavs
      301 arrgefgiip gsmgaksfiv rglgneesfc scshgagrvm srtkakklfs vddqiratah
      361 vecrkdadvi deipmaykdi davmaaqsdl veimyalrqv vcvkg