MULTISPECIES: virulence effector protease GtgE [Salmonella].

LOCUS       WP_001525490             228 aa            linear   BCT 29-JUL-2021
ACCESSION   WP_001525490
VERSION     WP_001525490.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 228)
  AUTHORS   Savitskiy,S., Wachtel,R., Pourjafar-Dehkordi,D., Kang,H.S.,
            Trauschke,V., Lamb,D.C., Sattler,M., Zacharias,M. and Itzen,A.
  TITLE     Proteolysis of Rab32 by Salmonella GtgE induces an inactive GTPase
            conformation
  JOURNAL   iScience 24 (1), 101940 (2020)
   PUBMED   33426511
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 228)
  AUTHORS   Wachtel,R., Brauning,B., Mader,S.L., Ecker,F., Kaila,V.R.I.,
            Groll,M. and Itzen,A.
  TITLE     The protease GtgE from Salmonella exclusively targets inactive Rab
            GTPases
  JOURNAL   Nat Commun 9 (1), 44 (2018)
   PUBMED   29298974
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 228)
  AUTHORS   Xu,C., Kozlov,G., Wong,K., Gehring,K. and Cygler,M.
  TITLE     Crystal Structure of the Salmonella Typhimurium Effector GtgE
  JOURNAL   PLoS One 11 (12), e0166643 (2016)
   PUBMED   27923041
  REMARK    Publication Status: Online-Only
REFERENCE   4  (residues 1 to 228)
  AUTHORS   Kohler,A.C., Spano,S., Galan,J.E. and Stebbins,C.E.
  TITLE     Structural and enzymatic characterization of a host-specificity
            determinant from Salmonella
  JOURNAL   Acta Crystallogr D Biol Crystallogr 70 (Pt 2), 384-391 (2014)
   PUBMED   24531472
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR014666
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..228
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..228
                     /gene="gtgE"
     Protein         1..228
                     /product="virulence effector protease GtgE"
                     /calculated_mol_wt=25933
     Region          41..214
                     /region_name="GtgE"
                     /note="Salmonella enterica effector protein GtgE; cd21501"
                     /db_xref="CDD:411070"
     Site            order(41..46,77..83,86,142,144..151,171,179,181..182,
                     185..186,194,202)
                     /site_type="other"
                     /note="Rab GTPase binding site [polypeptide binding]"
                     /db_xref="CDD:411070"
ORIGIN      
        1 mlrhiqnslg svyrsntatp qgqiihhrnf qsqfdttgnt lynncwvcsl nviksrdgnn
       61 ysaleditsd nqafnnileg idiiecenll kemnvqkipe sslftnikea lqaevfnstv
      121 eddfesfisy elqnhgplml irpslgsecl haecivgyds evkkvliyds mntspewqsn
      181 idvydkltla fndkyknedc sicglyydgv yepkplhsss wkdwctil