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MULTISPECIES: SPI-2 type III secretion system effector SifA


LOCUS       WP_001520468             336 aa            linear   BCT 10-SEP-2020
            [Salmonella].
ACCESSION   WP_001520468
VERSION     WP_001520468.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 336)
  AUTHORS   Ohlson,M.B., Huang,Z., Alto,N.M., Blanc,M.P., Dixon,J.E., Chai,J.
            and Miller,S.I.
  TITLE     Structure and function of Salmonella SifA indicate that its
            interactions with SKIP, SseJ, and RhoA family GTPases induce
            endosomal tubulation
  JOURNAL   Cell Host Microbe 4 (5), 434-446 (2008)
   PUBMED   18996344
REFERENCE   2  (residues 1 to 336)
  AUTHORS   Brown,N.F., Szeto,J., Jiang,X., Coombes,B.K., Finlay,B.B. and
            Brumell,J.H.
  TITLE     Mutational analysis of Salmonella translocated effector members
            SifA and SopD2 reveals domains implicated in translocation,
            subcellular localization and function
  JOURNAL   Microbiology (Reading, Engl.) 152 (Pt 8), 2323-2343 (2006)
   PUBMED   16849798
REFERENCE   3  (residues 1 to 336)
  AUTHORS   Boucrot,E., Henry,T., Borg,J.P., Gorvel,J.P. and Meresse,S.
  TITLE     The intracellular fate of Salmonella depends on the recruitment of
            kinesin
  JOURNAL   Science 308 (5725), 1174-1178 (2005)
   PUBMED   15905402
REFERENCE   4  (residues 1 to 336)
  AUTHORS   Brumell,J.H., Goosney,D.L. and Finlay,B.B.
  TITLE     SifA, a type III secreted effector of Salmonella typhimurium,
            directs Salmonella-induced filament (Sif) formation along
            microtubules
  JOURNAL   Traffic 3 (6), 407-415 (2002)
   PUBMED   12010459
REFERENCE   5  (residues 1 to 336)
  AUTHORS   Miao,E.A. and Miller,S.I.
  TITLE     A conserved amino acid sequence directing intracellular type III
            secretion by Salmonella typhimurium
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 97 (13), 7539-7544 (2000)
   PUBMED   10861017
REFERENCE   6  (residues 1 to 336)
  AUTHORS   Stein,M.A., Leung,K.Y., Zwick,M., Garcia-del Portillo,F. and
            Finlay,B.B.
  TITLE     Identification of a Salmonella virulence gene required for
            formation of filamentous structures containing lysosomal membrane
            glycoproteins within epithelial cells
  JOURNAL   Mol. Microbiol. 20 (1), 151-164 (1996)
   PUBMED   8861213
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR000679
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..336
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..336
                     /gene="sifA"
     Protein         1..336
                     /product="SPI-2 type III secretion system effector SifA"
                     /calculated_mol_wt=38367
     Region          1..336
                     /region_name="sifA"
                     /note="type III secretion system effector SifA; PRK09498"
                     /db_xref="CDD:181911"
ORIGIN      
        1 mpitigngfl kseiltnspr ntkeawwkvl wekikdfffs tgkakadrcl hemlfaerap
       61 trerlteiff elkelacasq rdrfqvhnph endatiilri mdqneenell ritqntdtfs
      121 cevmgnlyfl mkdrpdilks hpqmtamikr ryseivdypl pstlclnpag apilsvpldn
      181 iegylytelr kghldgwkaq ekatylaaki qsgiekttri lhhanisest qqnafletma
      241 mcglkqleip pphthipiek mvkevlladk tfqaflvtdp stsqsmlaei veaisdqvfh
      301 aifridpqai qkmaeeqltt lhvrseqqsg clccfl