translation initiation factor IF-2 [Escherichia coli].

LOCUS       WP_001459775             733 aa            linear   BCT 03-JUN-2024
ACCESSION   WP_001459775
VERSION     WP_001459775.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 733)
  AUTHORS   Roy,B., Liu,Q., Shoji,S. and Fredrick,K.
  TITLE     IF2 and unique features of initiator tRNAfMet help establish the
            translational reading frame
  JOURNAL   RNA Biol 15 (4-5), 604-613 (2018)
   PUBMED   28914580
REFERENCE   2  (residues 1 to 733)
  AUTHORS   Sacerdot,C., Vachon,G., Laalami,S., Morel-Deville,F., Cenatiempo,Y.
            and Grunberg-Manago,M.
  TITLE     Both forms of translational initiation factor IF2 (alpha and beta)
            are required for maximal growth of Escherichia coli. Evidence for
            two translational initiation codons for IF2 beta
  JOURNAL   J Mol Biol 225 (1), 67-80 (1992)
   PUBMED   1374802
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00487.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..733
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..733
                     /gene="infB"
     Protein         1..733
                     /product="translation initiation factor IF-2"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003743 - translation initiation factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_process="GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /calculated_mol_wt=79615
     Region          <13..>124
                     /region_name="PTZ00121"
                     /note="MAEBL; Provisional"
                     /db_xref="CDD:173412"
     Region          157..207
                     /region_name="IF2_N"
                     /note="Translation initiation factor IF-2, N-terminal
                     region; pfam04760"
                     /db_xref="CDD:428110"
     Region          231..732
                     /region_name="InfB"
                     /note="Translation initiation factor IF-2, a GTPase
                     [Translation, ribosomal structure and biogenesis];
                     COG0532"
                     /db_xref="CDD:440298"
ORIGIN      
        1 msnqqddmtk naqaekarre qeaaelkrka eeearrklee earrvaeear rmaeenkwtd
       61 naeptedssd yhvttsqhar qaedesdrev eggrgrgrna kaarpkkgnk haeskadree
      121 araavrggkg gkrkgsslqq gfqkpaqavn rdvvigetit vgelankmav kgsqvikamm
      181 klgamatinq vidqetaqlv aeemghkvil rreneleeav msdrdtgaaa eprapvvtim
      241 ghvdhgktsl ldyirstkva sgeaggitqh igayhveten gmitfldtpg haaftsmrar
      301 gaqatdivvl vvaaddgvmp qtieaiqhak aaqvpvvvav nkidkpeadp drvknelsqy
      361 gilpeewgge sqfvhvsaka gtgidellda illqaevlel kavrkgmasg aviesfldkg
      421 rgpvatvlvr egtlhkgdiv lcgfeygrvr amrnelgqev leagpsipve ilglsgvpaa
      481 gdevtvvrde kkarevalyr qgkfrevkla rqqksklenm fanmtegevh evnivlkadv
      541 qgsveaisds llklstdevk vkiigsgvgg itetdatlaa asnailvgfn vradasarkv
      601 ieaesldlry ysviynlide vkaamsgmls pelkqqiigl aevrdvfksp kfgaiagcmv
      661 tegvvkrhnp irvlrdnvvi yegeleslrr fkddvnevrn gmecgigvkn yndvrtgdvi
      721 evfeiieiqr tia