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LOCUS WP_001395589 373 aa linear BCT 21-FEB-2023 ACCESSION WP_001395589 VERSION WP_001395589.1 KEYWORDS RefSeq. SOURCE Shigella flexneri ORGANISM Shigella flexneri Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella. REFERENCE 1 (residues 1 to 373) AUTHORS Ante,V.M., Bina,X.R. and Bina,J.E. TITLE The LysR-type regulator LeuO regulates the acid tolerance response in Vibrio cholerae JOURNAL Microbiology (Reading) 161 (12), 2434-2443 (2015) PUBMED 26424466 REFERENCE 2 (residues 1 to 373) AUTHORS Landgraf,J.R., Boxer,J.A. and Calvo,J.M. TITLE Escherichia coli Lrp (leucine-responsive regulatory protein) does not directly regulate expression of the leu operon promoter JOURNAL J Bacteriol 181 (20), 6547-6551 (1999) PUBMED 10515950 REFERENCE 3 (residues 1 to 373) AUTHORS Haughn,G.W., Wessler,S.R., Gemmill,R.M. and Calvo,J.M. TITLE High A + T content conserved in DNA sequences upstream of leuABCD in Escherichia coli and Salmonella typhimurium JOURNAL J Bacteriol 166 (3), 1113-1117 (1986) PUBMED 3519576 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: HMM Evidence Accession :: NF007063.1 Evidence Source :: NCBI Protein Cluster (PRK) Source Identifier :: PRK09508 ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..373 /organism="Shigella flexneri" /db_xref="taxon:623" gene 1..373 /gene="leuO" Protein 1..373 /product="transcriptional regulator LeuO" /GO_function="GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]" /GO_process="GO:0006355 - regulation of DNA-templated transcription [Evidence IEA]" /calculated_mol_wt=42602 Region 60..373 /region_name="leuO" /note="leucine transcriptional activator; Reviewed; PRK09508" /db_xref="CDD:181918" ORIGIN 1 mthstamdsv firtrifmfs efysfcfflf ymhdksyssg lflcipirer elsvtvelsm 61 pevqtdhset aelskpqlrm vdlnlltvfd avmqeqnitr aahvlgmsqp avsnavarlk 121 vmfndelfvr ygrgiqptar afqlfgsvrq alqlvqnelp gsgfepasse rvfhlcvcsp 181 ldsiltsqiy nhieqiapni hvmfksslnq ntehqlryqe tefvisyedf hrpeftsvpl 241 fkdemvlvas knhptikgpl lkhdvyneqh aavsldrfas fsqpwydtvd kqasiayqgm 301 ammsvlsvvs qthlvaiapr wlaeefaesl elqvlplplk qnsrtcylsw heaagrdkgh 361 qwmeeqlvsi ckr