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transcriptional regulator LeuO [Shigella flexneri].


LOCUS       WP_001395589             373 aa            linear   BCT 21-FEB-2023
ACCESSION   WP_001395589
VERSION     WP_001395589.1
KEYWORDS    RefSeq.
SOURCE      Shigella flexneri
  ORGANISM  Shigella flexneri
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Shigella.
REFERENCE   1  (residues 1 to 373)
  AUTHORS   Ante,V.M., Bina,X.R. and Bina,J.E.
  TITLE     The LysR-type regulator LeuO regulates the acid tolerance response
            in Vibrio cholerae
  JOURNAL   Microbiology (Reading) 161 (12), 2434-2443 (2015)
   PUBMED   26424466
REFERENCE   2  (residues 1 to 373)
  AUTHORS   Landgraf,J.R., Boxer,J.A. and Calvo,J.M.
  TITLE     Escherichia coli Lrp (leucine-responsive regulatory protein) does
            not directly regulate expression of the leu operon promoter
  JOURNAL   J Bacteriol 181 (20), 6547-6551 (1999)
   PUBMED   10515950
REFERENCE   3  (residues 1 to 373)
  AUTHORS   Haughn,G.W., Wessler,S.R., Gemmill,R.M. and Calvo,J.M.
  TITLE     High A + T content conserved in DNA sequences upstream of leuABCD
            in Escherichia coli and Salmonella typhimurium
  JOURNAL   J Bacteriol 166 (3), 1113-1117 (1986)
   PUBMED   3519576
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF007063.1
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK09508
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..373
                     /organism="Shigella flexneri"
                     /db_xref="taxon:623"
     gene            1..373
                     /gene="leuO"
     Protein         1..373
                     /product="transcriptional regulator LeuO"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /calculated_mol_wt=42602
     Region          60..373
                     /region_name="leuO"
                     /note="leucine transcriptional activator; Reviewed;
                     PRK09508"
                     /db_xref="CDD:181918"
ORIGIN      
        1 mthstamdsv firtrifmfs efysfcfflf ymhdksyssg lflcipirer elsvtvelsm
       61 pevqtdhset aelskpqlrm vdlnlltvfd avmqeqnitr aahvlgmsqp avsnavarlk
      121 vmfndelfvr ygrgiqptar afqlfgsvrq alqlvqnelp gsgfepasse rvfhlcvcsp
      181 ldsiltsqiy nhieqiapni hvmfksslnq ntehqlryqe tefvisyedf hrpeftsvpl
      241 fkdemvlvas knhptikgpl lkhdvyneqh aavsldrfas fsqpwydtvd kqasiayqgm
      301 ammsvlsvvs qthlvaiapr wlaeefaesl elqvlplplk qnsrtcylsw heaagrdkgh
      361 qwmeeqlvsi ckr