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MULTISPECIES: DNA-binding transcriptional regulator AscG


LOCUS       WP_001394680             336 aa            linear   BCT 17-MAY-2020
            [Enterobacteriaceae].
ACCESSION   WP_001394680
VERSION     WP_001394680.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 336)
  AUTHORS   Hall,B.G. and Xu,L.
  TITLE     Nucleotide sequence, function, activation, and evolution of the
            cryptic asc operon of Escherichia coli K12
  JOURNAL   Mol. Biol. Evol. 9 (4), 688-706 (1992)
   PUBMED   1630307
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR011140
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..336
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..336
                     /gene="ascG"
     Protein         1..336
                     /product="DNA-binding transcriptional regulator AscG"
                     /calculated_mol_wt=36682
     Region          2..69
                     /region_name="HTH_LACI"
                     /note="helix_turn _helix lactose operon repressor;
                     smart00354"
                     /db_xref="CDD:197675"
     Site            order(13..17,19..20,23,28..29,32,45,48,51..52,54..55)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:143331"
     Site            45..54
                     /site_type="active"
                     /note="domain linker motif [active]"
                     /db_xref="CDD:143331"
     Region          61..329
                     /region_name="PBP1_GalS-like"
                     /note="ligand binding domain of DNA transcription
                     iso-repressor GalS, which is one of two regulatory
                     proteins involved in galactose transport and metabolism;
                     cd06270"
                     /db_xref="CDD:380494"
     Site            order(61,68,76,81,84,93..96,98,112,116,224..225,257,
                     283..284)
                     /site_type="other"
                     /note="dimer interface (closed form) [polypeptide
                     binding]"
                     /db_xref="CDD:380494"
     Site            order(75,124,197,222,248,276)
                     /site_type="other"
                     /note="ligand binding site [chemical binding]"
                     /db_xref="CDD:380494"
ORIGIN      
        1 mttmlevakr agvskatvsr vlsgngyvsq etkdrvfqav eesgyrpnll arnlsakstq
       61 tlglvvtntl yhgiyfsell fhaarmaeek grqllladgk hsaeeerqai qylldlrcda
      121 imiyprflsv deiddiidah sqpimvlnrr lrknsshsvw cdhkqtsfna vaelinaghq
      181 eiafltgsmd sptsierlag ykdalaqhgi alnekliang kwtpasgaeg vemllergak
      241 fsalvasndd maigamkalh ergvavpeqv svigfddiai apytvpalss vkipvtemiq
      301 eiigrlifml dggdfsppkt fsgklirrds liapsr