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LOCUS WP_001362609 317 aa linear BCT 26-FEB-2025 ACCESSION WP_001362609 VERSION WP_001362609.1 KEYWORDS RefSeq. SOURCE Escherichia coli ORGANISM Escherichia coli Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia. REFERENCE 1 (residues 1 to 317) AUTHORS Swint-Kruse,L. and Matthews,K.S. TITLE Allostery in the LacI/GalR family: variations on a theme JOURNAL Curr Opin Microbiol 12 (2), 129-137 (2009) PUBMED 19269243 REFERENCE 2 (residues 1 to 317) AUTHORS Fukami-Kobayashi,K., Tateno,Y. and Nishikawa,K. TITLE Parallel evolution of ligand specificity between LacI/GalR family repressors and periplasmic sugar-binding proteins JOURNAL Mol Biol Evol 20 (2), 267-277 (2003) PUBMED 12598694 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: HMM Evidence Accession :: NF024770.6 Evidence Source :: EMBL-EBI Source Identifier :: PF13377.12 ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..317 /organism="Escherichia coli" /db_xref="taxon:562" Protein 1..317 /product="substrate-binding domain-containing protein" /calculated_mol_wt=34915 Region 1..57 /region_name="HTH_XRE" /note="Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; cl22854" /db_xref="CDD:473980" Site 31..40 /site_type="active" /note="domain linker motif [active]" /db_xref="CDD:143331" Region 46..315 /region_name="Peripla_BP_1" /note="Periplasmic binding proteins and sugar binding domain of LacI family; pfam00532" /db_xref="CDD:395423" ORIGIN 1 mmtvsrvmhn aesvrpatrd rvlqaiqtln yvpdlsarkm raqgrkpstl avlaqdtatt 61 pfsvdillai eqtasefgwn sflinifsed daaraarqll ahrpdgiiyt tmglrhitlp 121 eslygenivl ancvaddpal psyipddyta qyestqhlla agyrqplcfw lpesalatgy 181 rrqgfeqawr dagrdlaevk qfhmatgddh ytdlasllnd hfksgkpdfd vlicgndraa 241 fvayqvllak gvripqdvav mgfdnlvgvg hlflppltti qlphdiigre aalhiiegre 301 ggsvtripcp llircst