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substrate-binding domain-containing protein [Escherichia coli].


LOCUS       WP_001362609             317 aa            linear   BCT 26-FEB-2025
ACCESSION   WP_001362609
VERSION     WP_001362609.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 317)
  AUTHORS   Swint-Kruse,L. and Matthews,K.S.
  TITLE     Allostery in the LacI/GalR family: variations on a theme
  JOURNAL   Curr Opin Microbiol 12 (2), 129-137 (2009)
   PUBMED   19269243
REFERENCE   2  (residues 1 to 317)
  AUTHORS   Fukami-Kobayashi,K., Tateno,Y. and Nishikawa,K.
  TITLE     Parallel evolution of ligand specificity between LacI/GalR family
            repressors and periplasmic sugar-binding proteins
  JOURNAL   Mol Biol Evol 20 (2), 267-277 (2003)
   PUBMED   12598694
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF024770.6
            Evidence Source    :: EMBL-EBI
            Source Identifier  :: PF13377.12
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..317
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     Protein         1..317
                     /product="substrate-binding domain-containing protein"
                     /calculated_mol_wt=34915
     Region          1..57
                     /region_name="HTH_XRE"
                     /note="Helix-turn-helix XRE-family like proteins.
                     Prokaryotic DNA binding proteins belonging to the
                     xenobiotic response element family of transcriptional
                     regulators; cl22854"
                     /db_xref="CDD:473980"
     Site            31..40
                     /site_type="active"
                     /note="domain linker motif [active]"
                     /db_xref="CDD:143331"
     Region          46..315
                     /region_name="Peripla_BP_1"
                     /note="Periplasmic binding proteins and sugar binding
                     domain of LacI family; pfam00532"
                     /db_xref="CDD:395423"
ORIGIN      
        1 mmtvsrvmhn aesvrpatrd rvlqaiqtln yvpdlsarkm raqgrkpstl avlaqdtatt
       61 pfsvdillai eqtasefgwn sflinifsed daaraarqll ahrpdgiiyt tmglrhitlp
      121 eslygenivl ancvaddpal psyipddyta qyestqhlla agyrqplcfw lpesalatgy
      181 rrqgfeqawr dagrdlaevk qfhmatgddh ytdlasllnd hfksgkpdfd vlicgndraa
      241 fvayqvllak gvripqdvav mgfdnlvgvg hlflppltti qlphdiigre aalhiiegre
      301 ggsvtripcp llircst