bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate

LOCUS       WP_001361504             180 aa            linear   BCT 19-JUN-2019
            guanylyltransferase [Escherichia coli].
ACCESSION   WP_001361504
VERSION     WP_001361504.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF004469.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK05800
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..180
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..180
                     /gene="cobU"
     Protein         1..180
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /EC_number="2.7.1.156"
                     /EC_number="2.7.7.62"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0043752 - adenosylcobinamide kinase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=19902
     Region          1..180
                     /region_name="cobU"
                     /note="adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase;
                     Validated; PRK05800"
                     /db_xref="CDD:235612"
     Site            order(7..9,11,135..138,140,151,155..156,158..159,162,173,
                     175)
                     /site_type="other"
                     /note="trimer interface [polypeptide binding]"
                     /db_xref="CDD:410861"
     Site            order(7..13,28,30..32,34,47,50,56,80..81,84)
                     /site_type="other"
                     /note="GTP binding site [chemical binding]"
                     /db_xref="CDD:410861"
     Site            46
                     /site_type="active"
                     /note="putative catalytic site [active]"
                     /db_xref="CDD:410861"
ORIGIN      
        1 milvtggars gksrhaeali gdssqvlyia tsqilddema ariehhrqgr pehwrtverw
       61 qhldelihad inpnevvlle cvttmvtnll fdyggdkdpd ewdyqameqa inaeiqslia
      121 acqrcpakvv lvtnevgmgi vpesrlarhf rdiagrvnqq laaaanevwl vvsgigvkik