trifunctional transcriptional regulator/proline

LOCUS       WP_001356407            1320 aa            linear   BCT 10-DEC-2019
            dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase
            [Escherichia coli].
ACCESSION   WP_001356407
VERSION     WP_001356407.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 1320)
  AUTHORS   Zhang,W., Zhou,Y. and Becker,D.F.
  TITLE     Regulation of PutA-membrane associations by flavin adenine
            dinucleotide reduction
  JOURNAL   Biochemistry 43 (41), 13165-13174 (2004)
   PUBMED   15476410
REFERENCE   2  (residues 1 to 1320)
  AUTHORS   Zhang,M., White,T.A., Schuermann,J.P., Baban,B.A., Becker,D.F. and
            Tanner,J.J.
  TITLE     Structures of the Escherichia coli PutA proline dehydrogenase
            domain in complex with competitive inhibitors
  JOURNAL   Biochemistry 43 (39), 12539-12548 (2004)
   PUBMED   15449943
REFERENCE   3  (residues 1 to 1320)
  AUTHORS   Gu,D., Zhou,Y., Kallhoff,V., Baban,B., Tanner,J.J. and Becker,D.F.
  TITLE     Identification and characterization of the DNA-binding domain of
            the multifunctional PutA flavoenzyme
  JOURNAL   J. Biol. Chem. 279 (30), 31171-31176 (2004)
   PUBMED   15155740
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008772.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK11809
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1320
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..1320
                     /gene="putA"
     Protein         1..1320
                     /product="trifunctional transcriptional regulator/proline
                     dehydrogenase/L-glutamate gamma-semialdehyde
                     dehydrogenase"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
                     /GO_function="GO:0003842 - 1-pyrroline-5-carboxylate
                     dehydrogenase activity [Evidence IEA]"
                     /GO_function="GO:0004657 - proline dehydrogenase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of transcription,
                     DNA-templated [Evidence IEA]"
                     /GO_process="GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=143699
     Region          1..1320
                     /region_name="putA"
                     /note="trifunctional transcriptional regulator/proline
                     dehydrogenase/pyrroline-5-carboxylate dehydrogenase;
                     Reviewed; PRK11809"
                     /db_xref="CDD:236989"
ORIGIN      
        1 mgtttmgvkl ddatreriks aatridrtph wlikqaifsy leqlensdtl pelpallsga
       61 anesdeaptp aeephqpfld faeqilpqsv sraaitaayr rpeteavsml leqarlpqpv
      121 aeqahklayq ladklrnqkn asgragmvqg llqefslssq egvalmclae allripdkat
      181 rdalirdkis ngnwqshigr spslfvnaat wgllftgklv sthneaslsr slnriigksg
      241 eplirkgvdm amrlmgeqfv tgetiaeala narkleekgf rysydmlgea altaadaqay
      301 mvsyqqaiha igkasngrgi yegpgisikl salhprysra qydrvmeely prlksltlla
      361 rqydiginid aeeadrleis ldlleklcfe pelagwngig fviqayqkrc plvidylidl
      421 atrsrrrlmi rlvkgaywds eikraqmdgl egypvytrkv ytdvsylaca kkllavpnli
      481 ypqfathnah tlaaiyqlag qnyypgqyef qclhgmgepl yeqvtgkvad gklnrpcriy
      541 apvgthetll aylvrrllen gantsfvnri adtslpldel vadpvtavek laqqegqtgl
      601 phpkiplprd lyghgrdnsa gldlanehrl aslssallns alqkwqalpm leqpvaagem
      661 spvinpaepk divgyvreat preveqales avnnapiwfa tppaeraail hraavlmesq
      721 mqqligilvr eagktfsnai aevreavdfl hyyagqvrdd fanethrplg pvvcispwnf
      781 plaiftgqia aalaagnsvl akpaeqtpli aaqgiaille agvppgvvql qpgrgetvga
      841 qltgddrvrg vmftgsteva tllqrniasr ldaqgrpipl iaetggmnam ivdssalteq
      901 vvidvlasaf dsagqrcsal rvlclqdeia dhtlkmlrga maecrmgnpg rlttdigpvi
      961 dseakanier hiqtmrskgr pvfqavrens edarewqsgt fvaptlield dfaelqkevf
     1021 gpvlhvvryn rnqlpelieq inasgygltl gvhtrideti aqvtgsahvg nlyvnrnmvg
     1081 avvgvqpfgg eglsgtgpka ggplylyrll anrpesalav tlarqdaeyp vdaqlkaalt
     1141 qplnalrewa anrpelqalc tqygelaqag tqrllpgptg erntwtllpr ervlciadde
     1201 qdaltqlaav lavgsqvlwp ddalhrqlvk alpstvseri qlakaenita qpfdavifhg
     1261 dsdqlralce avaardgaiv svqgfarges nillerlyie rslsvntaaa ggnaslmtig