Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

MULTISPECIES: crotonobetaine/carnitine-CoA ligase [Escherichia].


LOCUS       WP_001350478             517 aa            linear   BCT 20-NOV-2023
ACCESSION   WP_001350478
VERSION     WP_001350478.1
KEYWORDS    RefSeq.
SOURCE      Escherichia
  ORGANISM  Escherichia
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 517)
  AUTHORS   Meadows,J.A. and Wargo,M.J.
  TITLE     Carnitine in bacterial physiology and metabolism
  JOURNAL   Microbiology (Reading) 161 (6), 1161-1174 (2015)
   PUBMED   25787873
REFERENCE   2  (residues 1 to 517)
  AUTHORS   Bernal,V., Arense,P., Blatz,V., Mandrand-Berthelot,M.A., Canovas,M.
            and Iborra,J.L.
  TITLE     Role of betaine:CoA ligase (CaiC) in the activation of betaines and
            the transfer of coenzyme A in Escherichia coli
  JOURNAL   J Appl Microbiol 105 (1), 42-50 (2008)
   PUBMED   18266698
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF005947.1
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK08008
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..517
                     /organism="Escherichia"
                     /db_xref="taxon:561"
     gene            1..517
                     /gene="caiC"
     Protein         1..517
                     /product="crotonobetaine/carnitine-CoA ligase"
                     /EC_number="6.2.1.48"
                     /GO_function="GO:0016405 - CoA-ligase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009437 - carnitine metabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=58428
     Region          1..517
                     /region_name="caiC"
                     /note="putative crotonobetaine/carnitine-CoA ligase;
                     Validated; PRK08008"
                     /db_xref="CDD:181195"
ORIGIN      
        1 mdiiggqhlr qmwddladvy ghktalices sggvvnrysy lelnqeinrt anlfytlgir
       61 kgdkvalhld ncpefifcwf glakigaimv pinarllcee sawilqnsqa cllvtsaqfy
      121 pmyqqiqqed atqlrhiclt dvalpaddgv ssftqlknqq patlcyappl stddtaeilf
      181 tsgttsrpkg vvithynlrf agyysawqca lrdddvyltv mpafhidcqc taamaafsag
      241 atfvlvekys arafwgqvqk yratvtecip mmirtlmvqp psandqqhrl revmfylnls
      301 eqekdafcer fgvrlltsyg mtetivgiig drpgdkrrwp sigrvgfcye aeirddhnrp
      361 lpageigeic ikgipgktif keyflnpqat akvleadgwl htgdtgyrde edffyfvdrr
      421 cnmikrggen vscvelenii aahpkiqdiv vvgikdsird eaikafvvln egetlseeef
      481 frfceqnmak fkvpsyleir kdlprncsgk iirknlk