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trp operon repressor [Escherichia coli].


LOCUS       WP_001346115              98 aa            linear   BCT 19-MAR-2021
ACCESSION   WP_001346115
VERSION     WP_001346115.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 98)
  AUTHORS   Zhang,H., Zhao,D., Revington,M., Lee,W., Jia,X., Arrowsmith,C. and
            Jardetzky,O.
  TITLE     The solution structures of the trp repressor-operator DNA complex
  JOURNAL   J Mol Biol 238 (4), 592-614 (1994)
   PUBMED   8176748
REFERENCE   2  (residues 1 to 98)
  AUTHORS   Zhang,R.G., Joachimiak,A., Lawson,C.L., Schevitz,R.W.,
            Otwinowski,Z. and Sigler,P.B.
  TITLE     The crystal structure of trp aporepressor at 1.8 A shows how
            binding tryptophan enhances DNA affinity
  JOURNAL   Nature 327 (6123), 591-597 (1987)
   PUBMED   3600756
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01321.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..98
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..98
                     /gene="trpR"
     Protein         1..98
                     /product="trp operon repressor"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of transcription,
                     DNA-templated [Evidence IEA]"
                     /calculated_mol_wt=11189
     Region          1..98
                     /region_name="TrpR"
                     /note="Trp operon repressor [Transcription]; COG2973"
                     /db_xref="CDD:442212"
ORIGIN      
        1 maeqrhqewl rfvdllknay qndlhlplln lmltpderea lgtrvrivee llrgemsqre
       61 lknelgagia titrgsnslk aapvelrqwl eevllksd