MULTISPECIES: hemolysin HlyE [Enterobacteriaceae].

LOCUS       WP_001336523             303 aa            linear   BCT 14-JAN-2025
ACCESSION   WP_001336523
VERSION     WP_001336523.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 303)
  AUTHORS   Ogura,Y., Ooka,T., Asadulghani, Terajima,J., Nougayrede,J.P.,
            Kurokawa,K., Tashiro,K., Tobe,T., Nakayama,K., Kuhara,S.,
            Oswald,E., Watanabe,H. and Hayashi,T.
  TITLE     Extensive genomic diversity and selective conservation of
            virulence-determinants in enterohemorrhagic Escherichia coli
            strains of O157 and non-O157 serotypes
  JOURNAL   Genome Biol 8 (7), R138 (2007)
   PUBMED   17711596
REFERENCE   2  (residues 1 to 303)
  AUTHORS   Oscarsson,J., Westermark,M., Lofdahl,S., Olsen,B., Palmgren,H.,
            Mizunoe,Y., Wai,S.N. and Uhlin,B.E.
  TITLE     Characterization of a pore-forming cytotoxin expressed by
            Salmonella enterica serovars typhi and paratyphi A
  JOURNAL   Infect Immun 70 (10), 5759-5769 (2002)
   PUBMED   12228306
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008477.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK11376
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..303
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..303
                     /gene="hlyE"
     Protein         1..303
                     /product="hemolysin HlyE"
                     /GO_function="GO:0090729 - toxin activity [Evidence IEA]"
                     /GO_process="GO:0044179 - hemolysis in another organism
                     [Evidence IEA]"
                     /calculated_mol_wt=33627
     Region          1..303
                     /region_name="hlyE"
                     /note="hemolysin HlyE; PRK11376"
                     /db_xref="CDD:183107"
     Site            order(14,19..21,24..31,33,37,41,48,59,62..63,66..67,
                     70..71,74,77..78,81,85,89,92..93,96,100,111..112,115,
                     118..119,122,126,131,135,138..139,142..143,145..146,
                     149..150,153..154,157..158,160,164,168,171..172,175,210,
                     214,221,233,240,244,247..248,251,254..256,258..259,271,
                     273)
                     /site_type="other"
                     /note="oligomer interface [polypeptide binding]"
                     /db_xref="CDD:439354"
ORIGIN      
        1 mteivadktv evvknaieta dgaldlynky ldqvipwqtf detikelsrf kqeysqaasv
       61 lvgdiktllm dsqdkyfeat qtvyewcgva tqllaayill fdeynekkas aqkdilikvl
      121 ddgitklnea qksllvssqs fnnasgklla ldsqltndfs ekssyfqsqv dkirkeayag
      181 aaagvvagpf gliisysiaa gvvegklipe lknklksvqn ffttlsntvk qankdidaak
      241 lkltteiaai geiktetett rfyvdyddlm lsllkeaakk mintcneyqk rhgkktlfev
      301 pev