Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

dihydropteroate synthase [Shigella flexneri].


LOCUS       WP_001311155             297 aa            linear   BCT 19-JUN-2019
ACCESSION   WP_001311155
VERSION     WP_001311155.1
KEYWORDS    RefSeq.
SOURCE      Shigella flexneri
  ORGANISM  Shigella flexneri
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Shigella.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008625.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK11613
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..297
                     /organism="Shigella flexneri"
                     /db_xref="taxon:623"
     gene            1..297
                     /gene="folP"
     Protein         1..297
                     /product="dihydropteroate synthase"
                     /EC_number="2.5.1.15"
                     /GO_function="GO:0004156 - dihydropteroate synthase
                     activity [Evidence IEA]"
                     /calculated_mol_wt=32286
     Region          16..297
                     /region_name="folP"
                     /note="dihydropteroate synthase; Provisional; PRK11613"
                     /db_xref="CDD:183230"
     Site            order(37,111,130,132,154,200,232,236,270,272)
                     /site_type="other"
                     /note="substrate binding pocket [chemical binding]"
                     /db_xref="CDD:238380"
     Site            order(213,217..218,256,260,264,279..280)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:238380"
     Site            234..236
                     /site_type="active"
                     /note="inhibitor binding site [active]"
                     /db_xref="CDD:238380"
ORIGIN      
        1 mlrgfflsih trdnimklfa qgtsldlshp hvmgilnvtp dsfsdggthn slidavkhan
       61 lminagatii dvggestrpg aaevsveeel qrvipvveai aqrfevwisv dtskpevire
      121 sakvgahiin dirslsepga leaaaetglp vclmhmqgnp ktmqeapkyd dvfaevnryf
      181 ieqiarceqa giakekllld pgfgfgknls hnysllarla efhhfnlpll vgmsrksmig
      241 qllnvgpser lsgslacavi aamqgahiir vhdvketvea mrvveatlsa kenkrye