ribonuclease HI [Shigella flexneri].

LOCUS       WP_001310534             192 aa            linear   BCT 25-MAY-2020
ACCESSION   WP_001310534
VERSION     WP_001310534.1
KEYWORDS    RefSeq.
SOURCE      Shigella flexneri
  ORGANISM  Shigella flexneri
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Shigella.
REFERENCE   1  (residues 1 to 192)
  AUTHORS   Minias,A.E., Brzostek,A.M., Korycka-Machala,M., Dziadek,B.,
            Minias,P., Rajagopalan,M., Madiraju,M. and Dziadek,J.
  TITLE     RNase HI Is Essential for Survival of Mycobacterium smegmatis
  JOURNAL   PLoS ONE 10 (5), e0126260 (2015)
   PUBMED   25965344
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 192)
  AUTHORS   Ohtani,N., Haruki,M., Muroya,A., Morikawa,M. and Kanaya,S.
  TITLE     Characterization of ribonuclease HII from Escherichia coli
            overproduced in a soluble form
  JOURNAL   J. Biochem. 127 (5), 895-899 (2000)
   PUBMED   10788800
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF001236.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK00203
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..192
                     /organism="Shigella flexneri"
                     /db_xref="taxon:623"
     gene            1..192
                     /gene="rnhA"
     Protein         1..192
                     /product="ribonuclease HI"
                     /EC_number="3.1.26.4"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /calculated_mol_wt=21593
     Region          39..188
                     /region_name="rnhA"
                     /note="ribonuclease H; Reviewed; PRK00203"
                     /db_xref="CDD:178927"
     Site            order(47..50,80..82,85,107,157,175)
                     /site_type="other"
                     /note="RNA/DNA hybrid binding site [nucleotide binding]"
                     /db_xref="CDD:260010"
ORIGIN      
        1 mvsvsrtiwr viavliaviy vrlvvlqfds itgslpemlk qveiftdgsc lgnpgpggyg
       61 ailryrgrek tfsagytrtt nnrmelmaai valealkehc evilstdsqy vrqgitqwih
      121 nwkkrgwkta dkkpvknvdl wqrldaalgq hqikwewvkg haghpenerc delaraaamn
      181 ptledtgyqv ev