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DNA-binding transcriptional repressor LacI [Escherichia coli].


LOCUS       WP_001307621             363 aa            linear   BCT 24-FEB-2020
ACCESSION   WP_001307621
VERSION     WP_001307621.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 363)
  AUTHORS   Lewis,M., Chang,G., Horton,N.C., Kercher,M.A., Pace,H.C.,
            Schumacher,M.A., Brennan,R.G. and Lu,P.
  TITLE     Crystal structure of the lactose operon repressor and its complexes
            with DNA and inducer
  JOURNAL   Science 271 (5253), 1247-1254 (1996)
   PUBMED   8638105
REFERENCE   2  (residues 1 to 363)
  AUTHORS   Lehming,N., Sartorius,J., Niemoller,M., Genenger,G., v
            Wilcken-Bergmann,B. and Muller-Hill,B.
  TITLE     The interaction of the recognition helix of lac repressor with lac
            operator
  JOURNAL   EMBO J. 6 (10), 3145-3153 (1987)
   PUBMED   2826131
REFERENCE   3  (residues 1 to 363)
  AUTHORS   Riggs,A.D., Suzuki,H. and Bourgeois,S.
  TITLE     Lac repressor-operator interaction. I. Equilibrium studies
  JOURNAL   J. Mol. Biol. 48 (1), 67-83 (1970)
   PUBMED   4915295
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR011233
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..363
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..363
                     /gene="lacI"
     Protein         1..363
                     /product="DNA-binding transcriptional repressor LacI"
                     /calculated_mol_wt=38756
     Region          3..343
                     /region_name="lacI"
                     /note="lac repressor; Reviewed; PRK09526"
                     /db_xref="CDD:181929"
ORIGIN      
        1 mvnvkpvtly dvaeyagvsy qtvsrvvnqa shvsaktrek veaamaelny ipnrvaqqla
       61 gkqslligva tsslalhaps qivaaiksra dqlgasvvvs mversgveac kaavhnllaq
      121 rvsgliinyp lddqdaiave aacanvpalf ldvsdqtpin siifshedgt rlgvehlval
      181 ghqqiallag plssvsarlr lagwhkyltr nqiqpiaere gdwsamsgfq qtmqmlnegi
      241 vptamlvand qmalgamrai tesglrvgad isvvgyddte dsscyipplt tikqdfrllg
      301 qtsvdrllql sqgqavkgnq llpvslvkrk ttlapktqta spraladslm qlarqvsrle
      361 sgq