hypoxanthine phosphoribosyltransferase [Shigella flexneri].

LOCUS       WP_001307573             182 aa            linear   BCT 22-MAR-2022
ACCESSION   WP_001307573
VERSION     WP_001307573.1
KEYWORDS    RefSeq.
SOURCE      Shigella flexneri
  ORGANISM  Shigella flexneri
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Shigella.
REFERENCE   1  (residues 1 to 182)
  AUTHORS   Lee,C.C., Craig,S.P. 3rd and Eakin,A.E.
  TITLE     A single amino acid substitution in the human and a bacterial
            hypoxanthine phosphoribosyltransferase modulates specificity for
            the binding of guanine
  JOURNAL   Biochemistry 37 (10), 3491-3498 (1998)
   PUBMED   9521670
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01203.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..182
                     /organism="Shigella flexneri"
                     /db_xref="taxon:623"
     gene            1..182
                     /gene="hpt"
     Protein         1..182
                     /product="hypoxanthine phosphoribosyltransferase"
                     /EC_number="2.4.2.8"
                     /GO_process="GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /calculated_mol_wt=20486
     Region          5..182
                     /region_name="PRK15423"
                     /note="hypoxanthine phosphoribosyltransferase;
                     Provisional"
                     /db_xref="CDD:185321"
     Site            order(46,48,103..105,107..111,135)
                     /site_type="active"
                     /db_xref="CDD:206754"
ORIGIN      
        1 mvrdmkhtve vmipeaeika riaelgrqit erykdsgsdm vlvgllrgsf mfmadlcrev
       61 qvshevdfmt assygsgmst trdvkilkdl dedirgkdvl ivediidsgn tlskvreils
      121 lrepkslaic tlldkpsrre vnvpvefigf sipdefvvgy gidyaqryrh lpyigkvill
      181 de