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winged helix-turn-helix transcriptional regulator [Shigella


LOCUS       WP_001307543             156 aa            linear   BCT 24-DEC-2024
            flexneri].
ACCESSION   WP_001307543
VERSION     WP_001307543.1
KEYWORDS    RefSeq.
SOURCE      Shigella flexneri
  ORGANISM  Shigella flexneri
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Shigella.
REFERENCE   1  (residues 1 to 156)
  AUTHORS   Aravind,L., Anantharaman,V., Balaji,S., Babu,M.M. and Iyer,L.M.
  TITLE     The many faces of the helix-turn-helix domain: transcription
            regulation and beyond
  JOURNAL   FEMS Microbiol Rev 29 (2), 231-262 (2005)
   PUBMED   15808743
REFERENCE   2  (residues 1 to 156)
  AUTHORS   Shao,X. and Grishin,N.V.
  TITLE     Common fold in helix-hairpin-helix proteins
  JOURNAL   Nucleic Acids Res 28 (14), 2643-2650 (2000)
   PUBMED   10908318
REFERENCE   3  (residues 1 to 156)
  AUTHORS   Gajiwala,K.S. and Burley,S.K.
  TITLE     Winged helix proteins
  JOURNAL   Curr Opin Struct Biol 10 (1), 110-116 (2000)
   PUBMED   10679470
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10004391
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..156
                     /organism="Shigella flexneri"
                     /db_xref="taxon:623"
     Protein         1..156
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /calculated_mol_wt=17429
     Region          41..147
                     /region_name="HxlR"
                     /note="DNA-binding transcriptional regulator, HxlR family
                     [Transcription]; COG1733"
                     /db_xref="CDD:441339"
ORIGIN      
        1 mgslhrfvlc lntltpkltf skyvqkgkye msqvslsqql kegnlfaeqc psrevlkhvt
       61 srwgvlilva lregthrfsd lrrkiggvse kmlaqslqal eqdgflnria ypvvpphvey
      121 sltplgeqvs ekvaaladwi elnlpevlav rderaa