GmrSD restriction endonuclease domain-containing protein

LOCUS       WP_001304006             387 aa            linear   BCT 02-MAR-2025
            [Escherichia coli].
ACCESSION   WP_001304006
VERSION     WP_001304006.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 387)
  AUTHORS   Gao,H., Gong,X., Zhou,J., Zhang,Y., Duan,J., Wei,Y., Chen,L.,
            Deng,Z., Wang,J., Chen,S., Wu,G. and Wang,L.
  TITLE     Nicking mechanism underlying the DNA phosphorothioate-sensing
            antiphage defense by SspE
  JOURNAL   Nat Commun 13 (1), 6773 (2022)
   PUBMED   36351933
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 387)
  AUTHORS   Machnicka,M.A., Kaminska,K.H., Dunin-Horkawicz,S. and Bujnicki,J.M.
  TITLE     Phylogenomics and sequence-structure-function relationships in the
            GmrSD family of Type IV restriction enzymes
  JOURNAL   BMC Bioinformatics 16, 336 (2015)
   PUBMED   26493560
  REMARK    Publication Status: Online-Only
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF019151.6
            Evidence Source    :: EMBL-EBI
            Source Identifier  :: PF07510.16
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     Protein         1..387
                     /product="GmrSD restriction endonuclease domain-containing
                     protein"
                     /calculated_mol_wt=45204
     Region          71..383
                     /region_name="COG3586"
                     /note="Uncharacterized protein domain, C-terminal to
                     COG1479 DNAse/DNA nickase [General function prediction
                     only]"
                     /db_xref="CDD:442805"
ORIGIN      
        1 malgkesdks latafqdlre lkvdvaypfl lalyhdyknd dlshedflsi irliesyvfr
       61 ravcaiptns lnktfatfyk vinkekyles iqvhflnlps yrrfpnddef krelkvrdly
      121 nfrsrsywlr rlendkrrer veeftiehim pqnenlsakw reelgsdwqr ihkellhtlg
      181 nltltrynsr ysdrpfaekr diedgfkhsp lylniglgqc ekwdeaaiha radrlaelav
      241 qvwqapslpe evlavyrgqp enktsyslsd ypfladgshs rvlfdhlrde imrldagitq
      301 evlklyiafk aetnfvdvvp qksrlrlsln mqfhelvdpk giakdvtnvg rwgngdveig
      361 fsdlaqlpyi mglirqafek qmesalv