adenosylmethionine--8-amino-7-oxononanoate transaminase

LOCUS       WP_001303857             429 aa            linear   BCT 19-JUN-2019
            [Escherichia coli].
ACCESSION   WP_001303857
VERSION     WP_001303857.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF005940.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK07986
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..429
                     /gene="bioA"
     Protein         1..429
                     /product="adenosylmethionine--8-amino-7-oxononanoate
                     transaminase"
                     /EC_number="2.6.1.62"
                     /GO_function="GO:0004015 -
                     adenosylmethionine-8-amino-7-oxononanoate transaminase
                     activity [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=47151
     Region          1..428
                     /region_name="PRK07986"
                     /note="adenosylmethionine--8-amino-7-oxononanoate
                     transaminase; Validated"
                     /db_xref="CDD:181189"
     Site            order(111..113,144..145,147,211,245,247..248,274)
                     /site_type="active"
                     /note="inhibitor-cofactor binding pocket [active]"
                     /db_xref="CDD:99735"
     Site            order(112..113,144..145,211,245,248,274)
                     /site_type="other"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]"
                     /db_xref="CDD:99735"
     Site            274
                     /site_type="active"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99735"
ORIGIN      
        1 mttddlafdq rhiwhpytsm tsplpvypva saegcelils dgrrlvdgms swwaaihgyn
       61 hpqlnaamks qidamshvmf ggithapaie lcrklvamtp qplecvflad sgsvavevam
      121 kmalqywqak gearqhfltf rngyhgdtfg amsvcdpdns mhslwkgylp enlfapapqs
      181 rmdgewderd mvgfarlmaa hrheiaavii epivqgaggm rmyhpewlkr irkmcdregi
      241 lliadeiatg fgrtgklfac ehaeiapdil clgkaltggt mtlsatlttr evaetisnge
      301 agcfmhgptf mgnplacaaa naslailesg dwqqqvaaie vqlreqlapa rdaemvadvr
      361 vlgaigvvet trpvnmaalq kffveqgvwi rpfgkliylm ppyiilpqql qrltaavnra
      421 vqdetffcq