MULTISPECIES: bifunctional aconitate hydratase 2/2-methylisocitrate

LOCUS       WP_001303793             865 aa            linear   BCT 04-JUN-2024
            dehydratase [Enterobacteriaceae].
ACCESSION   WP_001303793
VERSION     WP_001303793.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 865)
  AUTHORS   Bradbury,A.J., Gruer,M.J., Rudd,K.E. and Guest,J.R.
  TITLE     The second aconitase (AcnB) of Escherichia coli
  JOURNAL   Microbiology (Reading) 142 (Pt 2), 389-400 (1996)
   PUBMED   8932712
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00117.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..865
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..865
                     /gene="acnB"
     Protein         1..865
                     /product="bifunctional aconitate hydratase
                     2/2-methylisocitrate dehydratase"
                     /EC_number="4.2.1.3"
                     /EC_number="4.2.1.99"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0003994 - aconitate hydratase activity
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster
                     binding [Evidence IEA]"
                     /GO_process="GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /calculated_mol_wt=93353
     Region          1..864
                     /region_name="AcnB"
                     /note="Aconitase B [Energy production and conversion];
                     COG1049"
                     /db_xref="CDD:440670"
ORIGIN      
        1 mleeyrkhva eraaegiapk pldanqmaal vellknppag eeeflldllt nrvppgvdea
       61 ayvkagflaa vakgeakspl ltpekaiell gtmqggynih plidalddak lapiaakals
      121 htllmfdnfy dveekakagn eyakqvmqsw adaewflnrp alaekltvtv fkvtgetntd
      181 dlspapdaws rpdiplhala mlknaregie pdqpgvvgpi kqiealqqkg fplayvgdvv
      241 gtgssrksat nsvlwfmgdd iphvpnkrgg glclggkiap iffntmedag alpievdvsn
      301 lnmgdvidvy pykgevrnhe tgellatfel ktdvlidevr aggripliig rglttkarea
      361 lglphsdvfr qakdvaesdr gfslaqkmvg racgvkgirp gaycepkmts vgsqdttgpm
      421 trdelkdlac lgfsadlvmq sfchtaaypk pvdvnthhtl pdfimnrggv slrpgdgvih
      481 swlnrmllpd tvgtggdsht rfpigisfpa gsglvafaaa tgvmpldmpe svlvrfkgkm
      541 qpgitlrdlv haiplyaikq glltvekkgk knifsgrile ieglpdlkve qafeltdasa
      601 ersaagctik lnkepiieyl nsnivllkwm iaegygdrrt lerriqgmek wlanpellea
      661 dadaeyaavi didladikep ilcapndpdd arplsavqge kidevfigsc mtnighfraa
      721 gklldahkgq lptrlwvapp trmdaaqlte egyysvfgks garieipgcs lcmgnqarva
      781 dgatvvstst rnfpnrlgtg anvflasael aavaaligkl ptpeeyqtyv aqvdktavdt
      841 yrylnfnqls qytekadgvi fqtav