Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

medium-chain fatty-acid--CoA ligase [Escherichia coli].


LOCUS       WP_001302824             548 aa            linear   BCT 08-JUN-2023
ACCESSION   WP_001302824
VERSION     WP_001302824.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF004758.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK06087
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..548
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..548
                     /gene="fadK"
     Protein         1..548
                     /product="medium-chain fatty-acid--CoA ligase"
                     /EC_number="6.2.1.-"
                     /calculated_mol_wt=60662
     Region          2..548
                     /region_name="PRK06087"
                     /note="medium-chain fatty-acid--CoA ligase"
                     /db_xref="CDD:180393"
     Site            order(193,196..201,203..204)
                     /site_type="other"
                     /note="acyl-activating enzyme (AAE) consensus motif"
                     /db_xref="CDD:341229"
     Site            order(196,311..312,332..337,417,429,432,443,525)
                     /site_type="other"
                     /note="putative AMP binding site [chemical binding]"
                     /db_xref="CDD:341229"
     Site            order(196,236..237,284,286..287,290,311..312,332..337,417,
                     429,432,440..443,506)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:341229"
     Site            order(236,286..287,290,311,440..442,499,506)
                     /site_type="other"
                     /note="putative CoA binding site [chemical binding]"
                     /db_xref="CDD:341229"
ORIGIN      
        1 mkvtltfneq rraayrqqgl wgdasladyw qqtarampdk iavvdnhgas ytysaldhaa
       61 sclanwmlak giesgdriaf qlpgwceftv iylaclkiga vsvpllpswr eaelvwvlnk
      121 cqakmfftpt lfkqtrpvdl ilplqnqlpq lqqivgvdkl apatsslsls qiiadntplt
      181 taitthgdel aavlftsgte glpkgvmlth nnilaseray carlnltwqd vfmmpaplgh
      241 atgflhgvta pfligarsvl ldiftpdacl alleqqrcsc mlgatpfvyd llnllekqpa
      301 dlsalrfflc ggttipkkva recqqrgikl lsvygstess phavvnlddp lsrfmhtdgy
      361 aaagveikvv ddarktlppg cegeeasrgp nvfmgyfdep eltaraldee gwyysgdlcr
      421 mdeagyikit grkkdiivrg genissreve dillqhpkih dacvvampde rlgerscayv
      481 vlkaphhsls leevvaffsr krvakykype hivvieklpr tasgkiqkfl lrkdimrrlt
      541 qdvceeie