ATP-dependent zinc metalloprotease FtsH [Escherichia coli].

LOCUS       WP_001302248             647 aa            linear   BCT 11-DEC-2019
ACCESSION   WP_001302248
VERSION     WP_001302248.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 647)
  AUTHORS   Krzywda,S., Brzozowski,A.M., Verma,C., Karata,K., Ogura,T. and
            Wilkinson,A.J.
  TITLE     The crystal structure of the AAA domain of the ATP-dependent
            protease FtsH of Escherichia coli at 1.5 A resolution
  JOURNAL   Structure 10 (8), 1073-1083 (2002)
   PUBMED   12176385
REFERENCE   2  (residues 1 to 647)
  AUTHORS   Krzywda,S., Brzozowski,A.M., Karata,K., Ogura,T. and Wilkinson,A.J.
  TITLE     Crystallization of the AAA domain of the ATP-dependent protease
            FtsH of Escherichia coli
  JOURNAL   Acta Crystallogr. D Biol. Crystallogr. 58 (Pt 6 Pt 2), 1066-1067
            (2002)
   PUBMED   12037319
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008004.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK10733
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..647
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..647
                     /gene="ftsH"
     Protein         1..647
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /EC_number="3.4.24.-"
                     /GO_function="GO:0004176 - ATP-dependent peptidase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /calculated_mol_wt=70895
     Region          4..647
                     /region_name="hflB"
                     /note="ATP-dependent zinc metalloprotease FtsH; PRK10733"
                     /db_xref="CDD:182683"
ORIGIN      
        1 msdmaknlil wlviavvlms vfqsfgpses ngrkvdystf lqevnndqvr earingrein
       61 vtkkdsnryt tyipvqdpkl ldnlltknvk vvgeppeeps llasifiswf pmllligvwi
      121 ffmrqmqggg gkgamsfgks karmltedqi kttfadvagc deakeevael veylrepsrf
      181 qklggkipkg vlmvgppgtg ktllakaiag eakvpfftis gsdfvemfvg vgasrvrdmf
      241 eqakkaapci ifideidavg rqrgaglggg hdereqtlnq mlvemdgfeg negiiviaat
      301 nrpdvldpal lrpgrfdrqv vvglpdvrgr eqilkvhmrr vplapdidaa iiargtpgfs
      361 gadlanlvne aalfaargnk rvvsmvefek akdkimmgae rrsmvmteaq kestayheag
      421 haiigrlvpe hdpvhkvtii prgralgvtf flpegdaisa srqklesqis tlyggrlaee
      481 iiygpehvst gasndikvat nlarnmvtqw gfseklgpll yaeeegevfl grsvakakhm
      541 sdetariidq evkalierny nrarqlltdn mdilhamkda lmkyetidap qiddlmarrd
      601 vrppagweep gasnnagdng spkaprpvde prtpnpgntm seqlgdk