DNA-binding transcriptional regulator AscG [Escherichia coli].

LOCUS       WP_001302219             337 aa            linear   BCT 10-FEB-2020
ACCESSION   WP_001302219
VERSION     WP_001302219.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 337)
  AUTHORS   Hall,B.G. and Xu,L.
  TITLE     Nucleotide sequence, function, activation, and evolution of the
            cryptic asc operon of Escherichia coli K12
  JOURNAL   Mol. Biol. Evol. 9 (4), 688-706 (1992)
   PUBMED   1630307
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR011140
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..337
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..337
                     /gene="ascG"
     Protein         1..337
                     /product="DNA-binding transcriptional regulator AscG"
                     /calculated_mol_wt=36796
     Region          3..70
                     /region_name="HTH_LACI"
                     /note="helix_turn _helix lactose operon repressor;
                     smart00354"
                     /db_xref="CDD:197675"
     Site            order(14..18,20..21,24,29..30,33,46,49,52..53,55..56)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:143331"
     Site            46..55
                     /site_type="active"
                     /note="domain linker motif [active]"
                     /db_xref="CDD:143331"
     Region          62..330
                     /region_name="PBP1_GalS-like"
                     /note="ligand binding domain of DNA transcription
                     iso-repressor GalS, which is one of two regulatory
                     proteins involved in galactose transport and metabolism;
                     cd06270"
                     /db_xref="CDD:380494"
     Site            order(62,69,77,82,85,94..97,99,113,117,225..226,258,
                     284..285)
                     /site_type="other"
                     /note="dimer interface (closed form) [polypeptide
                     binding]"
                     /db_xref="CDD:380494"
     Site            order(76,125,198,223,249,277)
                     /site_type="other"
                     /note="ligand binding site [chemical binding]"
                     /db_xref="CDD:380494"
ORIGIN      
        1 mmttmlevak ragvskatvs rvlsgngyvs qetkdrvfqa veesgyrpnl larnlsakst
       61 qtlglvvtnt lyhgiyfsel lfhaarmaee kgrqllladg khsaeeerqa iqylldlrcd
      121 aimiyprfls vdeiddiida hsqpimvlnr rlrknsshsv wcdhkqtsfn avaelinagh
      181 qeiafltgsm dsptsverla gykdalaqhg ialneklian gkwtpasgae gvetllerga
      241 kfsalvasnd dmaigamkal hkrgvavpeq vsvigfddia iapyivpals svkipvtemi
      301 qeiigrlifm ldggdfsppk tfsgklirrd slialsr