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bestrophin family protein [Escherichia coli].


LOCUS       WP_001302151             304 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_001302151
VERSION     WP_001302151.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 304)
  AUTHORS   Qu,Z. and Hartzell,H.C.
  TITLE     Bestrophin Cl- channels are highly permeable to HCO3-
  JOURNAL   Am J Physiol Cell Physiol 294 (6), C1371-C1377 (2008)
   PUBMED   18400985
REFERENCE   2  (residues 1 to 304)
  AUTHORS   Tsunenari,T., Sun,H., Williams,J., Cahill,H., Smallwood,P.,
            Yau,K.W. and Nathans,J.
  TITLE     Structure-function analysis of the bestrophin family of anion
            channels
  JOURNAL   J Biol Chem 278 (42), 41114-41125 (2003)
   PUBMED   12907679
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10007980
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..304
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     Protein         1..304
                     /product="bestrophin family protein"
                     /GO_function="GO:0005254 - chloride channel activity
                     [Evidence IEA]"
                     /calculated_mol_wt=34692
     Region          1..303
                     /region_name="YneE"
                     /note="Predicted membrane chloride channel, bestrophin
                     family [Inorganic ion transport and metabolism]; COG3781"
                     /db_xref="CDD:442995"
ORIGIN      
        1 mivrpqqhwl rrifvwhgsv lskissrlll nflfsiavif mlpwythlgi kftlapfsil
       61 gvaiaiflgf rnnagyaryv earklwgqlm iasrsllrev kttlpdsasv refarlqiaf
      121 ahclrmtlrk qpqvevlahy lktedlqrvl asnspanril limgewlavq rrngqlsdil
      181 fislndrlnd isavlagcer iaytpipfay tlilhrtvyl fcimlpfalv vdlhymtpfi
      241 svlisytfis ldclaeeled pfgtenndlp ldaicnaiei dllqmndeae ipakvlpdrh
      301 yqlt