Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

HigA family addiction module antitoxin [Escherichia coli].


LOCUS       WP_001302113              94 aa            linear   BCT 25-OCT-2021
ACCESSION   WP_001302113
VERSION     WP_001302113.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 94)
  AUTHORS   Wood,T.L. and Wood,T.K.
  TITLE     The HigB/HigA toxin/antitoxin system of Pseudomonas aeruginosa
            influences the virulence factors pyochelin, pyocyanin, and biofilm
            formation
  JOURNAL   Microbiologyopen 5 (3), 499-511 (2016)
   PUBMED   26987441
REFERENCE   2  (residues 1 to 94)
  AUTHORS   Budde,P.P., Davis,B.M., Yuan,J. and Waldor,M.K.
  TITLE     Characterization of a higBA toxin-antitoxin locus in Vibrio
            cholerae
  JOURNAL   J Bacteriol 189 (2), 491-500 (2007)
   PUBMED   17085558
REFERENCE   3  (residues 1 to 94)
  AUTHORS   Tian,Q.B., Ohnishi,M., Murata,T., Nakayama,K., Terawaki,Y. and
            Hayashi,T.
  TITLE     Specific protein-DNA and protein-protein interaction in the hig
            gene system, a plasmid-borne proteic killer gene system of plasmid
            Rts1
  JOURNAL   Plasmid 45 (2), 63-74 (2001)
   PUBMED   11322821
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR02607.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..94
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     Protein         1..94
                     /product="HigA family addiction module antitoxin"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /calculated_mol_wt=10182
     Region          5..79
                     /region_name="antidote_HigA"
                     /note="addiction module antidote protein, HigA family;
                     TIGR02607"
                     /db_xref="CDD:274228"
ORIGIN      
        1 mkmanhprpg diiqesldel nvslrefara meiapstasr lltgkaaltp emaiklsvvi
       61 gsspqmwlnl qnawslaeaa ktvdvsrlrr lvaq