CDP-alcohol phosphatidyltransferase family protein [Escherichia

LOCUS       WP_001302100             206 aa            linear   BCT 01-JAN-2025
            coli].
ACCESSION   WP_001302100
VERSION     WP_001302100.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 206)
  AUTHORS   Nogly,P., Gushchin,I., Remeeva,A., Esteves,A.M., Borges,N., Ma,P.,
            Ishchenko,A., Grudinin,S., Round,E., Moraes,I., Borshchevskiy,V.,
            Santos,H., Gordeliy,V. and Archer,M.
  TITLE     X-ray structure of a CDP-alcohol phosphatidyltransferase membrane
            enzyme and insights into its catalytic mechanism
  JOURNAL   Nat Commun 5, 4169 (2014)
   PUBMED   24942835
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 206)
  AUTHORS   Sciara,G., Clarke,O.B., Tomasek,D., Kloss,B., Tabuso,S.,
            Byfield,R., Cohn,R., Banerjee,S., Rajashankar,K.R., Slavkovic,V.,
            Graziano,J.H., Shapiro,L. and Mancia,F.
  TITLE     Structural basis for catalysis in a CDP-alcohol phosphotransferase
  JOURNAL   Nat Commun 5, 4068 (2014)
   PUBMED   24923293
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 206)
  AUTHORS   Koga,Y.
  TITLE     From promiscuity to the lipid divide: on the evolution of distinct
            membranes in Archaea and Bacteria
  JOURNAL   J Mol Evol 78 (3-4), 234-242 (2014)
   PUBMED   24573438
REFERENCE   4  (residues 1 to 206)
  AUTHORS   Koga,Y.
  TITLE     Early evolution of membrane lipids: how did the lipid divide occur?
  JOURNAL   J Mol Evol 72 (3), 274-282 (2011)
   PUBMED   21259003
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10001704
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..206
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     Protein         1..206
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /EC_number="2.7.8.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity,
                     for other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic
                     process [Evidence IEA]"
                     /calculated_mol_wt=22574
     Region          28..205
                     /region_name="PgsA"
                     /note="Phosphatidylglycerophosphate synthase [Lipid
                     transport and metabolism]; COG0558"
                     /db_xref="CDD:440324"
ORIGIN      
        1 mldrhlhpri kpllhqcvrv ldkpgitpdg ltlvgfaigv lalpflalgw ylaalvvill
       61 nrlldgldga larrrgltda ggfldisldf lfyalvpfgf ilaapqqnal aggwllfafi
      121 gtgssflafa alaakyqidn pgyahksfyy lggltegtet illfvlgclf pawfawfawi
      181 fgalcwmttf trvwsgyltl kslqrq