EAL domain-containing protein [Escherichia coli].

LOCUS       WP_001302042             532 aa            linear   BCT 19-FEB-2025
ACCESSION   WP_001302042
VERSION     WP_001302042.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 532)
  AUTHORS   Simm,R., Morr,M., Kader,A., Nimtz,M. and Romling,U.
  TITLE     GGDEF and EAL domains inversely regulate cyclic di-GMP levels and
            transition from sessility to motility
  JOURNAL   Mol Microbiol 53 (4), 1123-1134 (2004)
   PUBMED   15306016
REFERENCE   2  (residues 1 to 532)
  AUTHORS   D'Argenio,D.A. and Miller,S.I.
  TITLE     Cyclic di-GMP as a bacterial second messenger
  JOURNAL   Microbiology (Reading) 150 (Pt 8), 2497-2502 (2004)
   PUBMED   15289546
REFERENCE   3  (residues 1 to 532)
  AUTHORS   Galperin,M.Y., Nikolskaya,A.N. and Koonin,E.V.
  TITLE     Novel domains of the prokaryotic two-component signal transduction
            systems
  JOURNAL   FEMS Microbiol Lett 203 (1), 11-21 (2001)
   PUBMED   11557134
  REMARK    Erratum:[FEMS Microbiol Lett 2001 Oct 16;204(1):213-4]
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11471819
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..532
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     Protein         1..532
                     /product="EAL domain-containing protein"
                     /EC_number="3.1.4.52"
                     /GO_component="GO:0005886 - plasma membrane [Evidence
                     IEA]"
                     /GO_function="GO:0071111 - cyclic-guanylate-specific
                     phosphodiesterase activity [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /calculated_mol_wt=59613
     Region          9..522
                     /region_name="YjcC"
                     /note="Redox-sensing c-di-GMP phosphodiesterase, contains
                     CSS-motif and EAL domains [Signal transduction
                     mechanisms]; COG4943"
                     /db_xref="CDD:443970"
ORIGIN      
        1 mqkaqriikt yrrnrmivct icalvtlast lsvrfisqrn lnqqrvvqfa nhaveeldkv
       61 llplqagsev llpliglpcs vahlplrkqa aklqtvrsig lvqdgtlycs sifgyrnvpv
      121 vdilaelpap qpllrlttdr vlikgspvli qwtpaasssn agvmeminid lltamllepq
      181 lpqissaslt vdkrhllygn glvdslpqpe dnenyqvssq rfsftinvng pgapalawhy
      241 lptqlplavl lsllvgyiaw latayrmsfs reinlglaqh efelfcqpll narsqqcigv
      301 eillrwnnpr qgwispdvfi piaeehhliv pltryvmaet irqrhvfpms sqfhvginva
      361 pshfrrgvli kdlnqywfsa hpiqqlilei terdalldvd yriarelhrk nvklaiddfg
      421 tgnssfswle tlrpdvlkid ksftaaigsd avnstvtdii ialgqrlnie lvaegvetqe
      481 qakylrrhgv hilqgylyaq pmplrdfpkw lagsqpppar hnghitpimp lr