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MULTISPECIES: acetolactate synthase small subunit [Escherichia].


LOCUS       WP_001301948             163 aa            linear   BCT 11-DEC-2019
ACCESSION   WP_001301948
VERSION     WP_001301948.1
KEYWORDS    RefSeq.
SOURCE      Escherichia
  ORGANISM  Escherichia
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 163)
  AUTHORS   Kaplun,A., Vyazmensky,M., Zherdev,Y., Belenky,I., Slutzker,A.,
            Mendel,S., Barak,Z., Chipman,D.M. and Shaanan,B.
  TITLE     Structure of the regulatory subunit of acetohydroxyacid synthase
            isozyme III from Escherichia coli
  JOURNAL   J. Mol. Biol. 357 (3), 951-963 (2006)
   PUBMED   16458324
REFERENCE   2  (residues 1 to 163)
  AUTHORS   Choi,K.J., Yu,Y.G., Hahn,H.G., Choi,J.D. and Yoon,M.Y.
  TITLE     Characterization of acetohydroxyacid synthase from Mycobacterium
            tuberculosis and the identification of its new inhibitor from the
            screening of a chemical library
  JOURNAL   FEBS Lett. 579 (21), 4903-4910 (2005)
   PUBMED   16111681
REFERENCE   3  (residues 1 to 163)
  AUTHORS   Porat,I., Vinogradov,M., Vyazmensky,M., Lu,C.D., Chipman,D.M.,
            Abdelal,A.T. and Barak,Z.
  TITLE     Cloning and characterization of acetohydroxyacid synthase from
            Bacillus stearothermophilus
  JOURNAL   J. Bacteriol. 186 (2), 570-574 (2004)
   PUBMED   14702326
REFERENCE   4  (residues 1 to 163)
  AUTHORS   Atkins,T., Prior,R.G., Mack,K., Russell,P., Nelson,M., Oyston,P.C.,
            Dougan,G. and Titball,R.W.
  TITLE     A mutant of Burkholderia pseudomallei, auxotrophic in the branched
            chain amino acid biosynthetic pathway, is attenuated and protective
            in a murine model of melioidosis
  JOURNAL   Infect. Immun. 70 (9), 5290-5294 (2002)
   PUBMED   12183585
REFERENCE   5  (residues 1 to 163)
  AUTHORS   Garault,P., Letort,C., Juillard,V. and Monnet,V.
  TITLE     Branched-chain amino acid biosynthesis is essential for optimal
            growth of Streptococcus thermophilus in milk
  JOURNAL   Appl. Environ. Microbiol. 66 (12), 5128-5133 (2000)
   PUBMED   11097879
REFERENCE   6  (residues 1 to 163)
  AUTHORS   Gardner,W.L. and Whitman,W.B.
  TITLE     Expression vectors for Methanococcus maripaludis: overexpression of
            acetohydroxyacid synthase and beta-galactosidase
  JOURNAL   Genetics 152 (4), 1439-1447 (1999)
   PUBMED   10430574
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008864.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK11895
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..163
                     /organism="Escherichia"
                     /db_xref="taxon:561"
     gene            1..163
                     /gene="ilvN"
     Protein         1..163
                     /product="acetolactate synthase small subunit"
                     /EC_number="2.2.1.6"
                     /GO_function="GO:1990610 - acetolactate synthase regulator
                     activity [Evidence IEA]"
                     /GO_process="GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /calculated_mol_wt=17930
     Region          1..162
                     /region_name="ilvH"
                     /note="acetolactate synthase 3 regulatory subunit;
                     Reviewed; PRK11895"
                     /db_xref="CDD:183365"
ORIGIN      
        1 mrrilsvlle nesgalsrvi glfsqrgyni esltvaptdd ptlsrmtiqt vgdekvleqi
       61 ekqlyklvdv lrvselgqga hvereimlvk iqasgygrde vkrnteifrg qiidvtpsly
      121 tvqlagtsdk ldaflasird vakivevars gvvglsrgdk imr