Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]
LOCUS WP_001301938 229 aa linear BCT 06-NOV-2024 ACCESSION WP_001301938 VERSION WP_001301938.1 KEYWORDS RefSeq. SOURCE Escherichia coli ORGANISM Escherichia coli Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia. REFERENCE 1 (residues 1 to 229) AUTHORS Arif,T., Currie,M.J., Dobson,R.C.J., Newson,H.L., Poonthiyil,V., Fairbanks,A.J., North,R.A. and Rendle,P.M. TITLE Synthesis of N-acetylmannosamine-6-phosphate derivatives to investigate the mechanism of N-acetylmannosamine-6-phosphate 2-epimerase JOURNAL Carbohydr Res 510, 108445 (2021) PUBMED 34607125 REFERENCE 2 (residues 1 to 229) AUTHORS Currie,M.J., Manjunath,L., Horne,C.R., Rendle,P.M., Subramanian,R., Friemann,R., Fairbanks,A.J., Muscroft-Taylor,A.C., North,R.A. and Dobson,R.C.J. TITLE N-acetylmannosamine-6-phosphate 2-epimerase uses a novel substrate-assisted mechanism to catalyze amino sugar epimerization JOURNAL J Biol Chem 297 (4), 101113 (2021) PUBMED 34437902 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: Conserved Domain (CDD) Evidence Accession :: Domain architecture ID 10011628 Evidence Source :: NCBI SPARCLE ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..229 /organism="Escherichia coli" /db_xref="taxon:562" Protein 1..229 /product="N-acetylmannosamine-6-phosphate 2-epimerase" /EC_number="5.1.3.9" /GO_function="GO:0047465 - N-acylglucosamine-6-phosphate 2-epimerase activity [Evidence IEA]" /GO_process="GO:0005975 - carbohydrate metabolic process [Evidence IEA]" /GO_process="GO:0006051 - N-acetylmannosamine metabolic process [Evidence IEA]" /GO_process="GO:0019262 - N-acetylneuraminate catabolic process [Evidence IEA]" /calculated_mol_wt=24028 Region 11..226 /region_name="PRK01130" /note="putative N-acetylmannosamine-6-phosphate 2-epimerase" /db_xref="CDD:234907" Site order(20,22,51,72,74,105,132,153,157,184..186,207) /site_type="active" /note="putative active site cavity [active]" /db_xref="CDD:240080" ORIGIN 1 msllaqldqk iaangglivs cqpvpdspld kpeivaamal aaeqagavai riegvanlqa 61 travvsvpii givkrdleds pvritayied vdalaqagad iiaidgtdrp rpvpvetlla 121 rihhhgllam tdcstpedgl acqklgaeii gttlsgyttp etpeepdltl vkrlsdagcr 181 viaegryntp aqaadamrhg awavtvgsai trlehicqwy ntamkkavl