crotonobetaine/carnitine-CoA ligase [Escherichia coli].

LOCUS       WP_001301863             517 aa            linear   BCT 07-MAR-2022
ACCESSION   WP_001301863
VERSION     WP_001301863.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 517)
  AUTHORS   Meadows,J.A. and Wargo,M.J.
  TITLE     Carnitine in bacterial physiology and metabolism
  JOURNAL   Microbiology (Reading) 161 (6), 1161-1174 (2015)
   PUBMED   25787873
REFERENCE   2  (residues 1 to 517)
  AUTHORS   Bernal,V., Arense,P., Blatz,V., Mandrand-Berthelot,M.A., Canovas,M.
            and Iborra,J.L.
  TITLE     Role of betaine:CoA ligase (CaiC) in the activation of betaines and
            the transfer of coenzyme A in Escherichia coli
  JOURNAL   J Appl Microbiol 105 (1), 42-50 (2008)
   PUBMED   18266698
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF005947.1
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK08008
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..517
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..517
                     /gene="caiC"
     Protein         1..517
                     /product="crotonobetaine/carnitine-CoA ligase"
                     /EC_number="6.2.1.48"
                     /GO_function="GO:0016405 - CoA-ligase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009437 - carnitine metabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=58483
     Region          1..517
                     /region_name="caiC"
                     /note="putative crotonobetaine/carnitine-CoA ligase;
                     Validated; PRK08008"
                     /db_xref="CDD:181195"
ORIGIN      
        1 mdiiggqhlr qmwddladvy ghktalices sggvvnrysy lelnqeinrt anlfytlgir
       61 kgdkvalhld ncpefifcwf glakigaimv pinarllree sawilqnsqa cllvtsaqfy
      121 pmyqqiqqed atqlrhiclt dvalpaddgv ssftqlknqq patlcyappl stddtaeilf
      181 tsgttsrpkg vvithynlrf agyysawqca lrdddvyltv mpafhidcqc taamaafsag
      241 atfvlvekys arafwgqvqk yratitecip mmirtlmvqp psandrqhrl revmfylnls
      301 eqekdtfcer fgvrlltsyg mtetivgiig drpgdkrrwp sigragfcyd aeirddhnrp
      361 lpageigeic ikgvpgktif keyflnpkat akvleadgwl htgdtgyrde egffyfidrr
      421 cnmikrggen vscvelenii athpkiqdiv vvgikdsird eaikafvvln egetlseeef
      481 frfceqnmak fkvpsyleir kdlprncsgk iirknlk