cytosine/isoguanine deaminase [Escherichia coli].

LOCUS       WP_001301830             427 aa            linear   BCT 11-FEB-2021
ACCESSION   WP_001301830
VERSION     WP_001301830.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 427)
  AUTHORS   Hitchcock,D.S., Fedorov,A.A., Fedorov,E.V., Dangott,L.J., Almo,S.C.
            and Raushel,F.M.
  TITLE     Rescue of the orphan enzyme isoguanine deaminase
  JOURNAL   Biochemistry 50 (25), 5555-5557 (2011)
   PUBMED   21604715
REFERENCE   2  (residues 1 to 427)
  AUTHORS   Hall,R.S., Fedorov,A.A., Xu,C., Fedorov,E.V., Almo,S.C. and
            Raushel,F.M.
  TITLE     Three-dimensional structure and catalytic mechanism of cytosine
            deaminase
  JOURNAL   Biochemistry 50 (22), 5077-5085 (2011)
   PUBMED   21545144
REFERENCE   3  (residues 1 to 427)
  AUTHORS   Porter,D.J. and Austin,E.A.
  TITLE     Cytosine deaminase. The roles of divalent metal ions in catalysis
  JOURNAL   J Biol Chem 268 (32), 24005-24011 (1993)
   PUBMED   8226944
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR011148
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..427
                     /gene="codA"
     Protein         1..427
                     /product="cytosine/isoguanine deaminase"
                     /EC_number="3.5.4.1"
                     /calculated_mol_wt=47493
     Region          2..427
                     /region_name="PRK09230"
                     /note="cytosine deaminase; Provisional"
                     /db_xref="CDD:181713"
     Site            order(62,64,215,218,247,314)
                     /site_type="active"
                     /db_xref="CDD:238618"
ORIGIN      
        1 msnnalqtii narlpgkegl wqihlqdgki saidaqsgvm pitensldae qglvippfve
       61 phihldttqt agqpnwnqsg tlfegierwa erkallthdd vkqrawqtlk wqiangiqhv
      121 rthvdvsdat ltalkamlev klevapwidl qivafpqegi lsypngeall eealrlgadv
      181 vgaiphfeft reygveslhk tfalaqkydr lidvhcdeid deqsrfvetv aalahregmg
      241 arvtashtta mhsyngayts rlfrllkmsg infvanplvn ihlqgrfdty pkrrgitrvk
      301 emlesginvc fghddvfdpw yplgtanmlq vlhmglhvcq lmgygqindg lnlithhsar
      361 tlnlqdysia agnsanliil paengfdalr rqvpvrysvr ggkviastqp aqttvyleqp
      421 eaidykr