iron-siderophore ABC transporter substrate-binding protein

LOCUS       WP_001301797             315 aa            linear   BCT 19-FEB-2025
            [Escherichia coli].
ACCESSION   WP_001301797
VERSION     WP_001301797.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 315)
  AUTHORS   Braun,V. and Braun,M.
  TITLE     Active transport of iron and siderophore antibiotics
  JOURNAL   Curr Opin Microbiol 5 (2), 194-201 (2002)
   PUBMED   11934617
REFERENCE   2  (residues 1 to 315)
  AUTHORS   Clarke,T.E., Tari,L.W. and Vogel,H.J.
  TITLE     Structural biology of bacterial iron uptake systems
  JOURNAL   Curr Top Med Chem 1 (1), 7-30 (2001)
   PUBMED   11895294
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10100157
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     Protein         1..315
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /calculated_mol_wt=34357
     Region          36..302
                     /region_name="FhuD"
                     /note="Fe3+-siderophore binding domain FhuD. These
                     proteins have been shown to function as initial receptors
                     in ABC transport of Fe3+-siderophores in many eubacterial
                     species. They belong to the TroA-like superfamily of
                     helical backbone metal receptor proteins...; cd01146"
                     /db_xref="CDD:238566"
     Site            order(78,96..97,118,194)
                     /site_type="active"
                     /note="siderophore binding site [active]"
                     /db_xref="CDD:238566"
ORIGIN      
        1 mrlffsllil lsffaratep vqvftddlgr kvtvpahpkr ivslhdldit iplielgvpp
       61 vashgrtrpd gshfirsgal ltgvdfdnss iafigtadid ieaivaakpd liiteptrnt
      121 pierlekiap tvsidhlkgg apeiyrklae ltgtqsqlai lerryqaqin alkatldsqk
      181 itvsviqanq gkinvmhsyh slgrvlrdag frfppliesi peggrmdvsa erlpeldadf
      241 vfatwrgdtg gkpqdelaam ekvmpgwcqf ltacrsgryv lisreeaisn sfaslglmaa
      301 qiqsqiagrp lpeak