Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

thiamine ABC transporter substrate binding subunit [Escherichia


LOCUS       WP_001301693             327 aa            linear   BCT 26-JUL-2024
            coli].
ACCESSION   WP_001301693
VERSION     WP_001301693.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 327)
  AUTHORS   Webb,E., Claas,K. and Downs,D.
  TITLE     thiBPQ encodes an ABC transporter required for transport of
            thiamine and thiamine pyrophosphate in Salmonella typhimurium
  JOURNAL   J Biol Chem 273 (15), 8946-8950 (1998)
   PUBMED   9535878
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01276.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..327
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..327
                     /gene="thiB"
     Protein         1..327
                     /product="thiamine ABC transporter substrate binding
                     subunit"
                     /GO_component="GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA]"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0030975 - thiamine binding [Evidence
                     IEA]"
                     /GO_function="GO:0048502 - ABC-type thiamine transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0015888 - thiamine transport [Evidence
                     IEA]"
                     /calculated_mol_wt=36044
     Region          19..327
                     /region_name="thiB"
                     /note="thiamine ABC transporter, periplasmic binding
                     protein; TIGR01276"
                     /db_xref="CDD:130343"
     Site            order(162..163,196..198,215,217..218)
                     /site_type="other"
                     /note="chemical substrate binding site [chemical binding]"
                     /db_xref="CDD:270263"
ORIGIN      
        1 mlkkclplll lctapvfakp vltvytydsf aadwgpgpvv kkafeadcnc elklvaledg
       61 vsllnrlrme gknskadvvl gldnnlldaa sktglfaksg vaadavnvpg gwnndifvpf
      121 dygyfafvyd knklknppqs lkelvesdqn wrviyqdprt stpglglllw mqkvygddap
      181 qawqklakkt vtvtkgwsea yglflkgesd lvlsyttspa yhileekkdn yaaanfsegh
      241 ylqvevaart aaskqpelaq kflqfmvspa fqnaiptgnw mypvanvtlp agfekltkpa
      301 ttleftpaev aaqrqawise wqravsr