terminase large subunit [Escherichia coli].

LOCUS       WP_001301491             553 aa            linear   BCT 31-DEC-2024
ACCESSION   WP_001301491
VERSION     WP_001301491.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 553)
  AUTHORS   Fung,H.K.H., Grimes,S., Huet,A., Duda,R.L., Chechik,M., Gault,J.,
            Robinson,C.V., Hendrix,R.W., Jardine,P.J., Conway,J.F.,
            Baumann,C.G. and Antson,A.A.
  TITLE     Structural basis of DNA packaging by a ring-type ATPase from an
            archetypal viral system
  JOURNAL   Nucleic Acids Res 50 (15), 8719-8732 (2022)
   PUBMED   35947691
REFERENCE   2  (residues 1 to 553)
  AUTHORS   Xu,R.G., Jenkins,H.T., Chechik,M., Blagova,E.V., Lopatina,A.,
            Klimuk,E., Minakhin,L., Severinov,K., Greive,S.J. and Antson,A.A.
  TITLE     Viral genome packaging terminase cleaves DNA using the canonical
            RuvC-like two-metal catalysis mechanism
  JOURNAL   Nucleic Acids Res 45 (6), 3580-3590 (2017)
   PUBMED   28100693
REFERENCE   3  (residues 1 to 553)
  AUTHORS   Black,L.W.
  TITLE     DNA packaging in dsDNA bacteriophages
  JOURNAL   Annu Rev Microbiol 43, 267-292 (1989)
   PUBMED   2679356
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11468530
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..553
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     Protein         1..553
                     /product="terminase large subunit"
                     /EC_number="3.6.4.-"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0140657 - ATP-dependent activity
                     [Evidence IEA]"
                     /calculated_mol_wt=60870
     Region          1..551
                     /region_name="YmfN"
                     /note="Phage terminase-like protein, large subunit,
                     contains N-terminal HTH domain [Mobilome: prophages,
                     transposons]; COG4626"
                     /db_xref="CDD:443665"
ORIGIN      
        1 mipvwstacp dwaerlkkgl siipapiype qaahalaifk qlrivdapgs ptfgescaqw
       61 vfdlvaalfg sydaqtgvrh ikevfilipk knskstlaag immtalllnw rqaagytila
      121 ptvevaanaf npardmvrrd ddlddlcqvq thirtithrv tdttlkvvaa dpntvsgiks
      181 vgtlidelwl fgkqykaedm lreaigglas rpegfvvytt tqsneppagv frqklqyard
      241 vrdgkihdph flpvifehpp emvesgahll menlamvnpn lgysvdeafl yreyrkarea
      301 geeafrgfms khanveigla lrsdrwagad fweqqgrrvs lddilqradv vtvgidgggl
      361 ddllgmyvig rdretrewlg wghawaheta vvrrkseasr fqdlvacgdm tivrrvgddt
      421 aevaeyvrri heaelldhig idpsgvgqil dslaeagipd givvgisqgw klggaiktte
      481 rklaegvlvh gdqplmawcv gnarvepkgn ailitkqasg rgkidplmal fnavslmsln
      541 pepkkkeyav ffi