DNA base-flipping protein [Escherichia coli].

LOCUS       WP_001300427             129 aa            linear   BCT 21-JAN-2024
ACCESSION   WP_001300427
VERSION     WP_001300427.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 129)
  AUTHORS   Mazon,G., Philippin,G., Cadet,J., Gasparutto,D., Modesti,M. and
            Fuchs,R.P.
  TITLE     Alkyltransferase-like protein (eATL) prevents mismatch
            repair-mediated toxicity induced by O6-alkylguanine adducts in
            Escherichia coli
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 107 (42), 18050-18055 (2010)
   PUBMED   20921378
REFERENCE   2  (residues 1 to 129)
  AUTHORS   Mazon,G., Philippin,G., Cadet,J., Gasparutto,D. and Fuchs,R.P.
  TITLE     The alkyltransferase-like ybaZ gene product enhances nucleotide
            excision repair of O(6)-alkylguanine adducts in E. coli
  JOURNAL   DNA Repair (Amst.) 8 (6), 697-703 (2009)
   PUBMED   19269902
REFERENCE   3  (residues 1 to 129)
  AUTHORS   Chen,C.S., Korobkova,E., Chen,H., Zhu,J., Jian,X., Tao,S.C., He,C.
            and Zhu,H.
  TITLE     A proteome chip approach reveals new DNA damage recognition
            activities in Escherichia coli
  JOURNAL   Nat. Methods 5 (1), 69-74 (2008)
   PUBMED   18084297
REFERENCE   4  (residues 1 to 129)
  AUTHORS   Pearson,S.J., Ferguson,J., Santibanez-Koref,M. and Margison,G.P.
  TITLE     Inhibition of O6-methylguanine-DNA methyltransferase by an
            alkyltransferase-like protein from Escherichia coli
  JOURNAL   Nucleic Acids Res. 33 (12), 3837-3844 (2005)
   PUBMED   16027108
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR007790
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..129
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..129
                     /gene="atl"
     Protein         1..129
                     /product="DNA base-flipping protein"
                     /calculated_mol_wt=14318
     Region          28..129
                     /region_name="Atl1"
                     /note="Alkylated DNA nucleotide flippase Atl1,
                     participates in nucleotide excision repair, Ada-like
                     DNA-binding domain [Transcription]; COG3695"
                     /db_xref="CDD:442910"
     Site            order(33..34,52..53,61,64,66..67,69,72..73,75,83,88,95)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:119438"
     Site            order(52,83..84,86,110)
                     /site_type="active"
                     /db_xref="CDD:119438"
ORIGIN      
        1 mlvscamrlh sgvfpdyaek lpqeekmeke dsfpqrvwqi vaaipegyvt tygdvaklag
       61 spraarqvgg vlkrlpegst lpwhrvvnrh gtisltgpdl qrqrqallae gvmvsgsgqi
      121 dlqryrwny