MULTISPECIES: tyrosine-type recombinase/integrase

LOCUS       WP_001300279             333 aa            linear   BCT 01-MAR-2025
            [Enterobacteriaceae].
ACCESSION   WP_001300279
VERSION     WP_001300279.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 333)
  AUTHORS   Guo,F., Gopaul,D.N. and van Duyne,G.D.
  TITLE     Structure of Cre recombinase complexed with DNA in a site-specific
            recombination synapse
  JOURNAL   Nature 389 (6646), 40-46 (1997)
   PUBMED   9288963
REFERENCE   2  (residues 1 to 333)
  AUTHORS   Kwon,H.J., Tirumalai,R., Landy,A. and Ellenberger,T.
  TITLE     Flexibility in DNA recombination: structure of the lambda integrase
            catalytic core
  JOURNAL   Science 276 (5309), 126-131 (1997)
   PUBMED   9082984
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF012798.6
            Evidence Source    :: EMBL-EBI
            Source Identifier  :: PF00589.27
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..333
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     Protein         1..333
                     /product="tyrosine-type recombinase/integrase"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence
                     IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /calculated_mol_wt=37674
     Region          1..331
                     /region_name="DNA_BRE_C"
                     /note="DNA breaking-rejoining enzymes, C-terminal
                     catalytic domain; cl00213"
                     /db_xref="CDD:469662"
     Site            order(176..177,180,196,199..200,233,235,237,282..283,
                     286..287,289..290,300,310,313)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:271177"
     Site            order(204,277,280..281,312)
                     /site_type="active"
                     /db_xref="CDD:271177"
ORIGIN      
        1 msvrkipsgk wlcecypyga sgkrirkqfa tksealsyer rlmnsrvgde fqdgsgprls
       61 eliarwfemy gktlssgaer kvkleaicsr lgdpfasqfd knmfatyrer rlsgewnpkg
      121 kkklseatvn reqsylhavf aelkrlgews genpltgirk freeekelaf lyvdeierll
      181 iacdesrnkd lgvvvrigla tgarwseaeg lkqsqvlpgr itfvktkgkk nrtvpispql
      241 qamlpkkrga lfspcyeafd aaikrakiel pdgqlthvlr htfashfmmr ggnilvlqki
      301 lghsdikmtm ryahfapghl eaavelnpfd nrg