MULTISPECIES: IMP dehydrogenase [Enterobacteriaceae].

LOCUS       WP_001299507             488 aa            linear   BCT 04-JUN-2024
ACCESSION   WP_001299507
VERSION     WP_001299507.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 488)
  AUTHORS   Alexandre,T., Raynal,B. and Munier-Lehmann,H.
  TITLE     Two classes of bacterial IMPDHs according to their quaternary
            structures and catalytic properties
  JOURNAL   PLoS One 10 (2), e0116578 (2015)
   PUBMED   25706619
  REMARK    Erratum:[PLoS One. 2015;10(4):e0125884. Rayna, Bertrand [corrected
            to Raynal, Bertrand]. PMID: 25923221]
            Publication Status: Online-Only
REFERENCE   2  (residues 1 to 488)
  AUTHORS   Pimkin,M. and Markham,G.D.
  TITLE     The CBS subdomain of inosine 5'-monophosphate dehydrogenase
            regulates purine nucleotide turnover
  JOURNAL   Mol Microbiol 68 (2), 342-359 (2008)
   PUBMED   18312263
REFERENCE   3  (residues 1 to 488)
  AUTHORS   Zhang,R., Evans,G., Rotella,F.J., Westbrook,E.M., Beno,D.,
            Huberman,E., Joachimiak,A. and Collart,F.R.
  TITLE     Characteristics and crystal structure of bacterial
            inosine-5'-monophosphate dehydrogenase
  JOURNAL   Biochemistry 38 (15), 4691-4700 (1999)
   PUBMED   10200156
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01302.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..488
                     /gene="guaB"
     Protein         1..488
                     /product="IMP dehydrogenase"
                     /EC_number="1.1.1.205"
                     /GO_function="GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /calculated_mol_wt=51892
     Region          8..473
                     /region_name="IMPDH"
                     /note="IMP dehydrogenase / GMP reductase domain;
                     pfam00478"
                     /db_xref="CDD:459826"
ORIGIN      
        1 mlriakealt fddvllvpah stvlpntadl stqltktirl nipmlsaamd tvtearlaia
       61 laqeggigfi hknmsierqa eevrrvkkhe sgvvtdpqtv lptttlrevk elterngfag
      121 ypvvteenel vgiitgrdvr fvtdlnqpvs vymtpkerlv tvregearev vlakmhekrv
      181 ekalvvddef hligmitvkd fqkaerkpna ckdeqgrlrv gaavgagagn eervdalvaa
      241 gvdvllidss hghsegvlqr iretrakypd lqiiggnvat aagaralaea gcsavkvgig
      301 pgsicttriv tgvgvpqita vadavealeg tgipviadgg irfsgdiaka iaagasavmv
      361 gsmlagtees pgeielyqgr syksyrgmgs lgamskgssd ryfqsdnaad klvpegiegr
      421 vaykgrlkei ihqqmgglrs cmgltgcgti delrtkaefv risgagiqes hvhdvtitke
      481 spnyrlgs