class Ia ribonucleoside-diphosphate reductase subunit beta

LOCUS       WP_001299501             389 aa            linear   BCT 01-MAY-2023
            [Shigella flexneri].
ACCESSION   WP_001299501
VERSION     WP_001299501.1
KEYWORDS    RefSeq.
SOURCE      Shigella flexneri
  ORGANISM  Shigella flexneri
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Shigella.
REFERENCE   1  (residues 1 to 389)
  AUTHORS   Kolberg,M., Strand,K.R., Graff,P. and Andersson,K.K.
  TITLE     Structure, function, and mechanism of ribonucleotide reductases
  JOURNAL   Biochim Biophys Acta 1699 (1-2), 1-34 (2004)
   PUBMED   15158709
REFERENCE   2  (residues 1 to 389)
  AUTHORS   Eriksson,M., Jordan,A. and Eklund,H.
  TITLE     Structure of Salmonella typhimurium nrdF ribonucleotide reductase
            in its oxidized and reduced forms
  JOURNAL   Biochemistry 37 (38), 13359-13369 (1998)
   PUBMED   9748343
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF006576.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK09101
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..389
                     /organism="Shigella flexneri"
                     /db_xref="taxon:623"
     gene            1..389
                     /gene="nrdB"
     Protein         1..389
                     /product="class Ia ribonucleoside-diphosphate reductase
                     subunit beta"
                     /EC_number="1.17.4.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /calculated_mol_wt=44830
     Region          14..389
                     /region_name="nrdB"
                     /note="ribonucleotide-diphosphate reductase subunit beta;
                     Reviewed; PRK09101"
                     /db_xref="CDD:181647"
     Site            order(51,58,123..124,127,130..131,134,137,151..152,155)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:153108"
     Site            order(62,98,129,132,136,250..251,255)
                     /site_type="active"
                     /note="putative radical transfer pathway [active]"
                     /db_xref="CDD:153108"
     Site            order(98,129,132,218,252,255)
                     /site_type="other"
                     /note="diiron center [ion binding]"
                     /db_xref="CDD:153108"
     Site            136
                     /site_type="other"
                     /note="tyrosyl radical"
                     /db_xref="CDD:153108"
ORIGIN      
        1 mpypalnsqq dtlmayttfs qtkndqlkep mffgqpvnva rydqqkydif ekliekqlsf
       61 fwrpeevdvs rdridyqalp ehekhifisn lkyqtlldsi qgrspnvall plisipelet
      121 wvetwafset ihsrsythii rnivndpsvv fddivtneqi qkraegissy ydeliemtsy
      181 whllgegtht vngktvtvsl relkkklylc lmsvnaleai rfyvsfacsf afaerelmeg
      241 nakiirliar dealhltgtq hmlnllrsga ddpemaeiae eckqecydlf vqaaqqekdw
      301 adylfrdgsm iglnkdilcq yveyitnirm qavgldlpfq trsnpipwin twlvsdnvqv
      361 apqevevssy lvgqidaevd tddlsnfql