MULTISPECIES: tyrosine-type recombinase/integrase

LOCUS       WP_001299351             339 aa            linear   BCT 01-MAR-2025
            [Enterobacteriaceae].
ACCESSION   WP_001299351
VERSION     WP_001299351.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 339)
  AUTHORS   Guo,F., Gopaul,D.N. and van Duyne,G.D.
  TITLE     Structure of Cre recombinase complexed with DNA in a site-specific
            recombination synapse
  JOURNAL   Nature 389 (6646), 40-46 (1997)
   PUBMED   9288963
REFERENCE   2  (residues 1 to 339)
  AUTHORS   Kwon,H.J., Tirumalai,R., Landy,A. and Ellenberger,T.
  TITLE     Flexibility in DNA recombination: structure of the lambda integrase
            catalytic core
  JOURNAL   Science 276 (5309), 126-131 (1997)
   PUBMED   9082984
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF012798.6
            Evidence Source    :: EMBL-EBI
            Source Identifier  :: PF00589.27
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..339
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     Protein         1..339
                     /product="tyrosine-type recombinase/integrase"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence
                     IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /calculated_mol_wt=38739
     Region          171..330
                     /region_name="INT_Lambda_C"
                     /note="C-terminal catalytic domain of Lambda integrase, a
                     tyrosine-based site-specific recombinase; cd00800"
                     /db_xref="CDD:271181"
     Site            order(171,174..175,177..178,185)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:271181"
     Site            order(197,289,292,312,321)
                     /site_type="active"
                     /db_xref="CDD:271181"
ORIGIN      
        1 mgrprknkkd nvlpprvrsn gysyvwkpeg strsiglgrv rktsvakvwq nyelekaklh
       61 nimtvaklwh mfmdspafte laprtqkdyr qhqkallmvf gkvladnvkt eqvrifmdkr
      121 glesktqanh elaslsrvyg wgyergyvkn npckgvrkfs lkartvyitd eqyaaiyaea
      181 ipqlriamei sylcaarlgd vlelkwqdim dkgiyieqnk tgtkqikews prlrtaiqla
      241 rnvssctcey vinttkggkv iaktlnnwwn qakraaeqkv gvpfgcnfhd ikakgisdye
      301 gssrdkqifs ghktenqvli ydrktkitpt ldlplvvsk