cardiolipin synthase ClsC [Escherichia coli].

LOCUS       WP_001299031             473 aa            linear   BCT 29-FEB-2020
ACCESSION   WP_001299031
VERSION     WP_001299031.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 473)
  AUTHORS   Tan,B.K., Bogdanov,M., Zhao,J., Dowhan,W., Raetz,C.R. and Guan,Z.
  TITLE     Discovery of a cardiolipin synthase utilizing
            phosphatidylethanolamine and phosphatidylglycerol as substrates
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 109 (41), 16504-16509 (2012)
   PUBMED   22988102
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR011108
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..473
                     /gene="clsC"
     Protein         1..473
                     /product="cardiolipin synthase ClsC"
                     /EC_number="2.7.8.-"
                     /calculated_mol_wt=53535
     Region          24..184
                     /region_name="PLDc_ymdC_like_1"
                     /note="Putative catalytic domain, repeat 1, of Escherichia
                     coli uncharacterized protein ymdC and similar proteins;
                     cd09111"
                     /db_xref="CDD:197210"
     Site            order(130,132,145,147,163)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:197210"
     Site            130
                     /site_type="active"
                     /note="catalytic site [active]"
                     /db_xref="CDD:197210"
     Region          250..469
                     /region_name="PLDc_ymdC_like_2"
                     /note="Putative catalytic domain, repeat 2, of Escherichia
                     coli uncharacterized protein ymdC and similar proteins;
                     cd09113"
                     /db_xref="CDD:197212"
     Site            order(369,371,384,386,397)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:197212"
     Site            369
                     /site_type="active"
                     /note="catalytic site [active]"
                     /db_xref="CDD:197212"
ORIGIN      
        1 mprlasavlp lcsqhpgqcg lfplekslda faaryrlaem aehtldvqyy iwqddmsgrl
       61 lfsallaaak rgvrvrllld dnntpglddi lrlldshpri evrlfnpfsf rllrplgyit
      121 dfsrlnrrmh nksftvdgvv tlvggrnigd ayfgageepl fsdldvmaig pvvedvaddf
      181 arywycksvs plqqvldvpe gemadrielp aswhndamth rylrkmessp finhlvdgtl
      241 pliwaktrll sddpakgegk akrhsllpqr lfdimgspse ridiissyfv ptragvaqll
      301 rmvrkgvkia iltnslaand vavvhagyar wrkkllrygv elyelkptre qsstlhdrgi
      361 tgnsgaslha ktfsidgktv figsfnfdpr stllntemgf viesetlaql idkrfiqsqy
      421 daawqlrldr wgrinwvdrh akkeiilkke patsfwkrvm vrlasilpve wll