2-iminobutanoate/2-iminopropanoate deaminase [Shigella flexneri].

LOCUS       WP_001298042             141 aa            linear   BCT 07-MAR-2020
ACCESSION   WP_001298042
VERSION     WP_001298042.1
KEYWORDS    RefSeq.
SOURCE      Shigella flexneri
  ORGANISM  Shigella flexneri
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Shigella.
REFERENCE   1  (residues 1 to 141)
  AUTHORS   Lambrecht,J.A., Flynn,J.M. and Downs,D.M.
  TITLE     Conserved YjgF protein family deaminates reactive enamine/imine
            intermediates of pyridoxal 5'-phosphate (PLP)-dependent enzyme
            reactions
  JOURNAL   J. Biol. Chem. 287 (5), 3454-3461 (2012)
   PUBMED   22094463
REFERENCE   2  (residues 1 to 141)
  AUTHORS   Lambrecht,J.A., Browne,B.A. and Downs,D.M.
  TITLE     Members of the YjgF/YER057c/UK114 family of proteins inhibit
            phosphoribosylamine synthesis in vitro
  JOURNAL   J. Biol. Chem. 285 (45), 34401-34407 (2010)
   PUBMED   20817725
REFERENCE   3  (residues 1 to 141)
  AUTHORS   Christopherson,M.R., Schmitz,G.E. and Downs,D.M.
  TITLE     YjgF is required for isoleucine biosynthesis when Salmonella
            enterica is grown on pyruvate medium
  JOURNAL   J. Bacteriol. 190 (8), 3057-3062 (2008)
   PUBMED   18296521
REFERENCE   4  (residues 1 to 141)
  AUTHORS   Enos-Berlage,J.L., Langendorf,M.J. and Downs,D.M.
  TITLE     Complex metabolic phenotypes caused by a mutation in yjgF, encoding
            a member of the highly conserved YER057c/YjgF family of proteins
  JOURNAL   J. Bacteriol. 180 (24), 6519-6528 (1998)
   PUBMED   9851994
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR000841
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..141
                     /organism="Shigella flexneri"
                     /db_xref="taxon:623"
     gene            1..141
                     /gene="ridA"
     Protein         1..141
                     /product="2-iminobutanoate/2-iminopropanoate deaminase"
                     /calculated_mol_wt=15039
     Region          14..140
                     /region_name="YjgF_YER057c_UK114_family"
                     /note="YjgF, YER057c, and UK114 belong to a large family
                     of proteins present in bacteria, archaea, and eukaryotes
                     with no definitive function. The conserved domain is
                     similar in structure to chorismate mutase but there is no
                     sequence similarity and no...; cl10015"
                     /db_xref="CDD:447879"
     Site            order(30..31,34,36,39,41,43..44,83,85..86,88,90,101,104,
                     116..123,133,135,137)
                     /site_type="other"
                     /note="homotrimer interaction site [polypeptide binding]"
                     /db_xref="CDD:100004"
     Site            order(30,97,101,118,133)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:100004"
ORIGIN      
        1 msqtfyrcnk geimsktiat enapaaigpy vqgvdlgnmi itsgqipvnp ktgevpadva
       61 aqarqsldnv kaiveaaglk vgdivkttvf vkdlndfatv natyeaffte hnatfparsc
      121 vevarlpkdv kieieaiavr r