MULTISPECIES: cystathionine gamma-synthase [Gammaproteobacteria].

LOCUS       WP_001295694             386 aa            linear   BCT 16-JAN-2022
ACCESSION   WP_001295694
VERSION     WP_001295694.1
KEYWORDS    RefSeq.
SOURCE      Gammaproteobacteria
  ORGANISM  Gammaproteobacteria
            Bacteria; Pseudomonadati; Pseudomonadota.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF005961.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK08045
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..386
                     /organism="Gammaproteobacteria"
                     /db_xref="taxon:1236"
     gene            1..386
                     /gene="metB"
     Protein         1..386
                     /product="cystathionine gamma-synthase"
                     /EC_number="2.5.1.48"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0019346 - transsulfuration [Evidence IEA]"
                     /calculated_mol_wt=41419
     Region          1..386
                     /region_name="PRK08045"
                     /note="cystathionine gamma-synthase; Provisional"
                     /db_xref="CDD:169194"
     Site            order(29..32,34..35,46,48,74..75,77..78,101,106,109,197,
                     205,207,224,234,236..237,316)
                     /site_type="other"
                     /note="homodimer interface [polypeptide binding]"
                     /db_xref="CDD:99738"
     Site            order(75..77,101,144,173,195,197..198,207)
                     /site_type="active"
                     /note="substrate-cofactor binding pocket [active]"
                     /db_xref="CDD:99738"
     Site            order(75..77,101,173,176,195,197..198)
                     /site_type="other"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]"
                     /db_xref="CDD:99738"
     Site            198
                     /site_type="active"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99738"
ORIGIN      
        1 mtrkqatiav rsglnddeqy gcvvppihls stynftgfne prahdysrrg nptrdvvqra
       61 laeleggaga vltntgmsai hlvttvflkp gdllvaphdc yggsyrlfds lakrgcyrvl
      121 fvdqgdeqal raalaekpkl vlvespsnpl lrvvdiakic hlarevgavs vvdntflspa
      181 lqnplalgad lvlhsctkyl nghsdvvagv viakdpdvvt elawwannig vtggafdsyl
      241 llrglrtlvp rmelaqrnaq aivkylqtqp lvkklyhpsl penqgheiaa rqqkgfgaml
      301 sfeldgdeqt lrrflgglsl ftlaeslggv eslishaatm thagmapear aaagisetll
      361 ristgiedge dliadlengf raankg