MULTISPECIES: type I DNA topoisomerase [Enterobacteriaceae].

LOCUS       WP_001295576             865 aa            linear   BCT 28-FEB-2022
ACCESSION   WP_001295576
VERSION     WP_001295576.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01051.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..865
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..865
                     /gene="topA"
     Protein         1..865
                     /product="type I DNA topoisomerase"
                     /EC_number="5.6.2.1"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003917 - DNA topoisomerase type I
                     (single strand cut, ATP-independent) activity [Evidence
                     IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /calculated_mol_wt=97220
     Region          2..849
                     /region_name="PRK07561"
                     /note="DNA topoisomerase I subunit omega; Validated"
                     /db_xref="CDD:236048"
ORIGIN      
        1 mgkalvives pakaktinky lgsdyvvkss vghirdlpts gsaakksads tstktakkpk
       61 kdergalvnr mgvdpwhnwe ahyevlpgke kvvselkqla ekadhiylat dldregeaia
      121 whlreviggd darysrvvfn eitknairqa fnkpgelnid rvnaqqarrf mdrvvgymvs
      181 pllwkkiarg lsagrvqsva vrlvverere ikafvpeefw evdastttps gealalqvth
      241 qndkpfrpvn keqtqaavsl lekarysvle redkpttskp gapfitstlq qaastrlgfg
      301 vkktmmmaqr lyeagyitym rtdstnlsqd avnmvrgyis dnfgkkylpe spnqyasken
      361 sqeaheairp sdvnvmaesl kdmeadaqkl yqliwrqfva cqmtpakyds ttltvgagdf
      421 rlkargrilr fdgwtkvmpa lrkgdedril pavdkgdalt lveltpaqhf tkpparfsea
      481 slvkelekrg igrpstyasi istiqdrgyv rvenrrfyae kmgeivtdrl eenfrelmny
      541 dftaqmensl dqvanheaew kavldhffsd ftqqldkaek dpeeggmrpn qmvltsidcp
      601 tcgrkmgirt astgvflgcs gyalppkerc kttinlvpen evlnvleged aetnalrakr
      661 rcpkcgtamd sylidpkrkl hvcgnnptcd gyeieegefr ikgydgpive cekcgsemhl
      721 kmgrfgkyma ctneeckntr kilrngevap pkedpvplpe lpceksdayf vlrdgaagvf
      781 laantfpksr etraplveel yrfrdrlpek lryladapqq dpegnktmvr fsrktkqqyv
      841 ssekdgkatg wsafyvdgkw vegkk