MULTISPECIES: (2E,6E)-farnesyl-diphosphate-specific

LOCUS       WP_001295562             252 aa            linear   BCT 06-MAY-2023
            ditrans,polycis-undecaprenyl-diphosphate synthase
            [Enterobacteriaceae].
ACCESSION   WP_001295562
VERSION     WP_001295562.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 252)
  AUTHORS   Chang,S.Y., Ko,T.P., Chen,A.P., Wang,A.H. and Liang,P.H.
  TITLE     Substrate binding mode and reaction mechanism of undecaprenyl
            pyrophosphate synthase deduced from crystallographic studies
  JOURNAL   Protein Sci 13 (4), 971-978 (2004)
   PUBMED   15044730
REFERENCE   2  (residues 1 to 252)
  AUTHORS   Chang,S.Y., Ko,T.P., Liang,P.H. and Wang,A.H.
  TITLE     Catalytic mechanism revealed by the crystal structure of
            undecaprenyl pyrophosphate synthase in complex with sulfate,
            magnesium, and triton
  JOURNAL   J Biol Chem 278 (31), 29298-29307 (2003)
   PUBMED   12756244
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF007596.1
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK10240
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..252
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..252
                     /gene="ispU"
                     /gene_synonym="uppS"
     Protein         1..252
                     /product="(2E,6E)-farnesyl-diphosphate-specific
                     ditrans,polycis-undecaprenyl-diphosphate synthase"
                     /GO_function="GO:0002094 - polyprenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008834 -
                     di-trans,poly-cis-decaprenylcistransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0043164 - Gram-negative-bacterium-type
                     cell wall biogenesis [Evidence IEA]"
                     /calculated_mol_wt=28182
     Region          24..252
                     /region_name="PRK10240"
                     /note="(2E,6E)-farnesyl-diphosphate-specific
                     ditrans,polycis-undecaprenyl-diphosphate synthase"
                     /db_xref="CDD:182326"
     Site            order(24..29,38,42,46,49,68,76,80,87..88,91,140,193,199,
                     201)
                     /site_type="active"
                     /db_xref="CDD:259850"
     Site            order(147..148,150..151,154..155,171..173,176,187,
                     198..202,205..207,209..213,215)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:259850"
ORIGIN      
        1 mlsatqplse klpahgcrhv aiimdgngrw akkqgkiraf ghkagaksvr ravsfaanng
       61 iealtlyafs senwnrpaqe vsalmelfvw aldsevkslh rhnvrlriig dtsrfnsrlq
      121 erirksealt agntgltlni aanyggrwdi vqgvrqlaek vqqgnlqpdq ideemlnqhv
      181 cmhelapvdl virtggehri snfllwqiay aelyftdvlw pdfdeqdfeg alnafanrer
      241 rfggtepgde ta