MULTISPECIES: pyruvate kinase PykF [Enterobacteriaceae].

LOCUS       WP_001295403             470 aa            linear   BCT 16-DEC-2020
ACCESSION   WP_001295403
VERSION     WP_001295403.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 470)
  AUTHORS   Guerrero-Mendiola,C., Garcia-Trejo,J.J., Encalada,R., Saavedra,E.
            and Ramirez-Silva,L.
  TITLE     The contribution of two isozymes to the pyruvate kinase activity of
            Vibrio cholerae: One K+-dependent constitutively active and another
            K+-independent with essential allosteric activation
  JOURNAL   PLoS ONE 12 (7), e0178673 (2017)
   PUBMED   28686591
  REMARK    Publication Status: Online-Only
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF006664.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK09206
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..470
                     /gene="pykF"
     Protein         1..470
                     /product="pyruvate kinase PykF"
                     /EC_number="2.7.1.40"
                     /GO_function="GO:0004743 - pyruvate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /calculated_mol_wt=50599
     Region          1..470
                     /region_name="PRK09206"
                     /note="pyruvate kinase PykF"
                     /db_xref="CDD:181699"
     Site            order(3..4,60,62,70..73,158..159,165,168..172,187,195,202,
                     214,250,268..269,273,305,307,336,338..339,389,391,393,404,
                     407..408,410,412..414)
                     /site_type="active"
                     /note="domain interfaces [active]"
                     /db_xref="CDD:238178"
     Site            order(32,34,66,193,220,222,246,278)
                     /site_type="active"
                     /db_xref="CDD:238178"
ORIGIN      
        1 mkktkivcti gpkteseeml akmldagmnv mrlnfshgdy aehgqriqnl rnvmsktgkt
       61 aailldtkgp eirtmklegg ndvslkagqt ftfttdksvi gnsemvavty egfttdlsvg
      121 ntvlvddgli gmevtaiegn kvickvlnng dlgenkgvnl pgvsialpal aekdkqdlif
      181 gceqgvdfva asfirkrsdv ieirehlkah ggenihiisk ienqeglnnf deileasdgi
      241 mvargdlgve ipveevifaq kmmiekcira rkvvitatqm ldsmiknprp traeagdvan
      301 aildgtdavm lsgesakgky pleavsimat icertdrvmn srlefnndnr klriteavcr
      361 gavetaekld aplivvatqg gksaravrky fpdatilalt tnektahqlv lskgvvpqlv
      421 keitstddfy rlgkelalqs glahkgdvvv mvsgalvpsg ttntasvhvl