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MULTISPECIES: porphobilinogen synthase [Gammaproteobacteria].


LOCUS       WP_001295337             324 aa            linear   BCT 16-JAN-2022
ACCESSION   WP_001295337
VERSION     WP_001295337.1
KEYWORDS    RefSeq.
SOURCE      Gammaproteobacteria
  ORGANISM  Gammaproteobacteria
            Bacteria; Pseudomonadati; Pseudomonadota.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF009923.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK13384
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..324
                     /organism="Gammaproteobacteria"
                     /db_xref="taxon:1236"
     gene            1..324
                     /gene="hemB"
     Protein         1..324
                     /product="porphobilinogen synthase"
                     /EC_number="4.2.1.24"
                     /GO_function="GO:0004655 - porphobilinogen synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0033014 - tetrapyrrole biosynthetic
                     process [Evidence IEA]"
                     /calculated_mol_wt=35494
     Region          1..319
                     /region_name="PRK09283"
                     /note="porphobilinogen synthase"
                     /db_xref="CDD:236450"
     Site            order(9,12..13,24,48,51,140..141,168..169,198..200,219,
                     222,228,231..232,250..254,278,296,300,303)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:238226"
     Site            order(118,120,122,130,165,195,201,204..205,210,216,220,
                     247,270,273,312)
                     /site_type="active"
                     /db_xref="CDD:238226"
     Site            order(195,247)
                     /site_type="active"
                     /note="Schiff base residues [active]"
                     /db_xref="CDD:238226"
ORIGIN      
        1 mtdliqrprr lrkspalram feettlslnd lvlpifveee iddykaveam pgvmripekh
       61 lareierian agirsvmtfg ishhtdetgs dawredglva rmsrickqtv pemivmsdtc
      121 fceytshghc gvlcehgvdn datlenlgkq avvaaaagad fiapsaamdg qvqairqald
      181 aagfkdtaim systkfassf ygpfreaags alkgdrksyq mnpmnrreai reslldeaqg
      241 adclmvkpag ayldivrelr ertelpigay qvsgeyamik faalagaide ekvvleslgs
      301 ikragadlif syfaldlaek kilr