MULTISPECIES: adenosylmethionine--8-amino-7-oxononanoate

LOCUS       WP_001295303             429 aa            linear   BCT 16-DEC-2020
            transaminase [Enterobacteriaceae].
ACCESSION   WP_001295303
VERSION     WP_001295303.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF005940.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK07986
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..429
                     /gene="bioA"
     Protein         1..429
                     /product="adenosylmethionine--8-amino-7-oxononanoate
                     transaminase"
                     /EC_number="2.6.1.62"
                     /GO_function="GO:0004015 -
                     adenosylmethionine-8-amino-7-oxononanoate transaminase
                     activity [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=47205
     Region          1..428
                     /region_name="PRK07986"
                     /note="adenosylmethionine--8-amino-7-oxononanoate
                     transaminase; Validated"
                     /db_xref="CDD:181189"
     Site            order(111..113,144..145,147,211,245,247..248,274)
                     /site_type="active"
                     /note="inhibitor-cofactor binding pocket [active]"
                     /db_xref="CDD:99735"
     Site            order(112..113,144..145,211,245,248,274)
                     /site_type="other"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]"
                     /db_xref="CDD:99735"
     Site            274
                     /site_type="active"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99735"
ORIGIN      
        1 mttddlafdq rhiwhpytsm tsplpvypvv saegcelils dgrrlvdgms swwaaihgyn
       61 hpqlnaamks qidamshvmf ggithapaie lcrklvamtp qplecvflad sgsvavevam
      121 kmalqywqak gearqrfltf rngyhgdtfg amsvcdpdns mhslwkgylp enlfapapqs
      181 rmdgewderd mvgfarlmaa hrheiaavii epivqgaggm rmyhpewlkr irkicdregi
      241 lliadeiatg fgrtgklfac ehaeiapdil clgkaltggt mtlsatlttr evaetisnge
      301 agcfmhgptf mgnplacaaa naslailesg dwqqqvadie vqlreqlapa rdaemvadvr
      361 vlgaigvvet thpvnmaalq kffveqgvwi rpfgkliylm ppyiilpqql qrltaavnra
      421 vqdetffcq