MULTISPECIES: 23S rRNA pseudouridine(2605) synthase RluB

LOCUS       WP_001291216             290 aa            linear   BCT 10-MAR-2024
            [Enterobacteriaceae].
ACCESSION   WP_001291216
VERSION     WP_001291216.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 290)
  AUTHORS   Czudnochowski,N., Ashley,G.W., Santi,D.V., Alian,A., Finer-Moore,J.
            and Stroud,R.M.
  TITLE     The mechanism of pseudouridine synthases from a covalent complex
            with RNA, and alternate specificity for U2605 versus U2604 between
            close homologs
  JOURNAL   Nucleic Acids Res 42 (3), 2037-2048 (2014)
   PUBMED   24214967
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF007976.1
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK10700
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..290
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..290
                     /gene="rluB"
     Protein         1..290
                     /product="23S rRNA pseudouridine(2605) synthase RluB"
                     /EC_number="5.4.99.22"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0001522 - pseudouridine synthesis
                     [Evidence IEA]"
                     /calculated_mol_wt=32466
     Region          1..289
                     /region_name="PRK10700"
                     /note="23S rRNA pseudouridine(2605) synthase RluB"
                     /db_xref="CDD:182659"
ORIGIN      
        1 mseklqkvla raghgsrrei esiieagrvs vdgkiaklgd rvevtpglki ridghlisvr
       61 esaeqicrvl ayykpegelc trndpegrpt vfdrlpklrg arwiavgrld vntcglllft
      121 tdgelanrlm hpsreverey avrvfgqvdd aklrdlsrgv qledgpaafk tikfsggegi
      181 nqwynvtlte grnrevrrlw eavgvqvsrl irvrygdipl pkglprggwt eldlaqtnyl
      241 relvelppet sskvavekdr rrmkanqirr avkrhsqvsg grrsggrnng