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LOCUS WP_001286898 938 aa linear BCT 23-MAY-2024 ACCESSION WP_001286898 VERSION WP_001286898.1 KEYWORDS RefSeq. SOURCE Shigella ORGANISM Shigella Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae. REFERENCE 1 (residues 1 to 938) AUTHORS Fukunaga,R. and Yokoyama,S. TITLE Crystallization and preliminary X-ray crystallographic study of the editing domain of Thermus thermophilus isoleucyl-tRNA synthetase complexed with pre- and post-transfer editing-substrate analogues JOURNAL Acta Crystallogr D Biol Crystallogr 60 (Pt 10), 1900-1902 (2004) PUBMED 15388946 REFERENCE 2 (residues 1 to 938) AUTHORS Yanagisawa,T. and Kawakami,M. TITLE How does Pseudomonas fluorescens avoid suicide from its antibiotic pseudomonic acid?: Evidence for two evolutionarily distinct isoleucyl-tRNA synthetases conferring self-defense JOURNAL J Biol Chem 278 (28), 25887-25894 (2003) PUBMED 12672810 REFERENCE 3 (residues 1 to 938) AUTHORS Nakama,T., Nureki,O. and Yokoyama,S. TITLE Structural basis for the recognition of isoleucyl-adenylate and an antibiotic, mupirocin, by isoleucyl-tRNA synthetase JOURNAL J Biol Chem 276 (50), 47387-47393 (2001) PUBMED 11584022 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: HMM Evidence Accession :: TIGR00392.1 Evidence Source :: JCVI ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..938 /organism="Shigella" /db_xref="taxon:620" gene 1..938 /gene="ileS" Protein 1..938 /product="isoleucine--tRNA ligase" /EC_number="6.1.1.5" /GO_function="GO:0000166 - nucleotide binding [Evidence IEA]" /GO_function="GO:0004822 - isoleucine-tRNA ligase activity [Evidence IEA]" /GO_function="GO:0005524 - ATP binding [Evidence IEA]" /GO_process="GO:0006428 - isoleucyl-tRNA aminoacylation [Evidence IEA]" /calculated_mol_wt=104136 Region 4..930 /region_name="IleS" /note="Isoleucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; COG0060" /db_xref="CDD:439830" ORIGIN 1 msdykstlnl petgfpmrgd lakrepgmla rwtdddlygi iraakkgkkt filhdgppya 61 ngsihighsv nkilkdiivk skglsgydsp yvpgwdchgl pielkveqey gkpgekftaa 121 efrakcreya atqvdgqrkd firlgvlgdw shpyltmdfk teaniiralg kiignghlhk 181 gakpvhwcvd crsalaeaev eyydktspsi dvafqavdqd alkakfgvsn vngpislviw 241 tttpwtlpan raisiapdfd yalvqidgqa vilakdlves vmqrigvtdy tilgtvkgae 301 lellrfthpf mgfdvpailg dhvtldagtg avhtapghgp ddyvigqkyg letanpvgpd 361 gtylpgtypt ldgvnvfkan divvallqek gallhvekmq hsypccwrhk tpiifratpq 421 wfvsmdqkgl raqslkeikg vqwlpdwgqa riesmvanrp dwcisrqrtw gvpmslfvhk 481 dteelhprtl elmeevakrv evdgiqawwd ldakeilgde adqyvkvpdt ldvwfdsgst 541 hssvvdvrpe faghaadmyl egsdqhrgwf msslmistam kgkapyrqvl thgftvdgqg 601 rkmsksignt vspqdvmnkl gadilrlwva stdytgemav sdeilkraad syrrirntar 661 fllanlngfd pakdmvkpee mvvldrwavg cakaaqedil kayeaydfhe vvqrlmrfcs 721 vemgsfyldi ikdrqytaka dsvarrscqt alyhiaealv rwmapilsft adevwgylpg 781 erekyvftge wyeglfglad seamndafwd ellkvrgevn kvieqaradk kvggsleaav 841 tlyaepelaa kltalgdelr fvlltsgatv adyndapada qqsevlkglk valskaegek 901 cprcwhytqd vgkvaehaei cgrcvsnvag dgekrkfa