MULTISPECIES: tRNA pseudouridine(38-40) synthase TruA

LOCUS       WP_001283590             270 aa            linear   BCT 23-MAY-2024
            [Enterobacteriaceae].
ACCESSION   WP_001283590
VERSION     WP_001283590.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 270)
  AUTHORS   Hur,S. and Stroud,R.M.
  TITLE     How U38, 39, and 40 of many tRNAs become the targets for
            pseudouridylation by TruA
  JOURNAL   Mol Cell 26 (2), 189-203 (2007)
   PUBMED   17466622
REFERENCE   2  (residues 1 to 270)
  AUTHORS   Dong,X., Bessho,Y., Shibata,R., Nishimoto,M., Shirouzu,M.,
            Kuramitsu,S. and Yokoyama,S.
  TITLE     Crystal structure of tRNA pseudouridine synthase TruA from Thermus
            thermophilus HB8
  JOURNAL   RNA Biol 3 (3), 115-122 (2006)
   PUBMED   17114947
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00071.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..270
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..270
                     /gene="truA"
     Protein         1..270
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /EC_number="5.4.99.12"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0001522 - pseudouridine synthesis
                     [Evidence IEA]"
                     /GO_process="GO:0009451 - RNA modification [Evidence IEA]"
                     /calculated_mol_wt=30254
     Region          10..258
                     /region_name="TruA"
                     /note="tRNA U38,U39,U40 pseudouridine synthase TruA
                     [Translation, ribosomal structure and biogenesis];
                     COG0101"
                     /db_xref="CDD:439871"
ORIGIN      
        1 msdqqqppvy kialgieydg skyygwqrqn evrsvqekle kalsqvanep itvfcagrtd
       61 agvhgtgqvv hfettaqrkd aawtlgvnan lpgdiavrwv kavpddfhar fsatarryry
      121 iiynhrlrpa vlskgvthfy epldaermhr aaqcllgend ftsfravqcq srtpwrnvmh
      181 invtrhgpyv vvdikanafv hhmvrnivgs lmevgahnqp eswiaellaa kdrtlaaata
      241 kaeglylvav dypdrydlpk ppmgplflad